Nyctalopin antibody (AA 282-481)

Catalog No. ABIN6144979

Product Details anti-Nyctalopin Antibody

Target: Nyctalopin (NYX)

Binding Specificity: AA 282-481

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nyctalopin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: LLYLDRNSIA FVEEGAFQNL SGLLALHLNG NRLTVLAWVA FQPGFFLGRL FLFRNPWCCD CRLEWLRDWM EGSGRVTDVP CASPGSVAGL DLSQVTFGRS SDGLCVDPEE LNLTTSSPGP SPEPAATTVS RFSSLLSKLL APRVPVEEAA NTTGGLANAS LSDSLSSRGV GGAGRQPWFL LASCLLPSVA QHVVFGLQMD

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 282-481 of human NYX (NP_072089.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Nyctalopin

Target: Nyctalopin (NYX)

Alternative Name: NYX (NYX Products)

Synonyms: MGC84276 antibody, CLRP antibody, CSNB1 antibody, CSNB1A antibody, CSNB4 antibody, NBM1 antibody, CLNP antibody, nob antibody, RGD1561300 antibody, nyctalopin antibody, nyctalopin L homeolog antibody, uncharacterized LOC491837 antibody, NYX antibody, nyx.L antibody, LOC491837 antibody, nyx antibody, Nyx antibody

Background: The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins. Defects in this gene are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB). CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus and reduced visual acuity. The role of other SLRP proteins suggests that mutations in this gene disrupt developing retinal interconnections involving the ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB.,NYX,CLRP,CSNB1,CSNB1A,CSNB4,NBM1,Neuroscience,NYX

Molecular Weight: 52 kDa

Gene ID: 60506

UniProt: Q9GZU5