P2RX2 antibody (AA 60-320)

Catalog No. ABIN6145107

Product Details anti-P2RX2 Antibody

Target: P2RX2 (Purinergic Receptor P2X, Ligand Gated Ion Channel 2 (P2RX2))

Binding Specificity: AA 60-320

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P2RX2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VFIVQKSYQE SETGPESSII TKVKGITTSE HKVWDVEEYV KPPEGGSVFS IITRVEATHS QTQGTCPESI RVHNATCLSD ADCVAGELDM LGNGLRTGRC VPYYQGPSKT CEVFGWCPVE DGASVSQFLG TMAPNFTILI KNSIHYPKFH FSKGNIADRT DGYLKRCTFH EASDLYCPIF KLGFIVEKAG ESFTELAHKG GVIGVIINWD CDLDLPASEC NPKYSFRRLD PKHVPASSGY NFRFAKYYKI NGTTTRTLIK A

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 60-320 of human P2RX2 (NP_733782.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-P2RX2 antibody (ABIN6145107)

Zhang, Liu, Chen, Yang, Liu, Li, Wang, Li, Liu: "Microencapsulated Schwann cell transplantation inhibits P2X2/3 receptors overexpression in a sciatic nerve injury rat model with neuropathic pain." in: Neuroscience letters, Vol. 676, pp. 51-57, (2018) (PubMed).

Target Details for P2RX2

Target: P2RX2 (Purinergic Receptor P2X, Ligand Gated Ion Channel 2 (P2RX2))

Alternative Name: P2RX2 (P2RX2 Products)

Synonyms: DFNA41 antibody, P2X2 antibody, P2X2a antibody, P2x2 antibody, p2xr2 antibody, P2RX2 antibody, purinergic receptor P2X 2 antibody, purinergic receptor P2X, ligand-gated ion channel, 2 antibody, P2RX2 antibody, P2rx2 antibody, p2rx2 antibody

Background: The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Multiple transcript variants encoding distinct isoforms have been identified for this gene.,P2RX2,DFNA41,P2X2,Cancer,Endocrine & Metabolism,Neuroscience,P2RX2

Molecular Weight: 41 kDa/43 kDa/44 kDa/49 kDa/51 kDa/54 kDa

Gene ID: 22953

UniProt: Q9UBL9

Pathways: Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity