P2RY2 antibody (AA 278-377)

Catalog No. ABIN6145128

Product Details anti-P2RY2 Antibody

Target: P2RY2 (Purinergic Receptor P2Y, G-Protein Coupled, 2 (P2RY2))

Binding Specificity: AA 278-377

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P2RY2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: CHTLNAINMA YKVTRPLASA NSCLDPVLYF LAGQRLVRFA RDAKPPTGPS PATPARRRLG LRRSDRTDMQ RIEDVLGSSE DSRRTESTPA GSENTKDIRL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 278-377 of human P2RY2 (NP_788086.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for P2RY2

Target: P2RY2 (Purinergic Receptor P2Y, G-Protein Coupled, 2 (P2RY2))

Alternative Name: P2RY2 (P2RY2 Products)

Background: The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, found on many cell types, is activated by ATP and UTP and is reported to be overexpressed on some cancer cell types. It is involved in many cellular functions, such as proliferation, apoptosis and inflammation. Three transcript variants encoding the same protein have been identified for this gene.,P2RY2,HP2U,P2RU1,P2U,P2U1,P2UR,P2Y2,P2Y2R,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,P2RY2

Molecular Weight: 42 kDa

Gene ID: 5029

UniProt: P41231

Pathways: Cellular Response to Molecule of Bacterial Origin, Smooth Muscle Cell Migration