PACS1 antibody (AA 420-560)

Catalog No. ABIN6145155

Product Details anti-PACS1 Antibody

Target: PACS1 (phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))

Binding Specificity: AA 420-560

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PACS1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SKGSLGKDTT SPMELAALEK IKSTWIKNQD DSLTETDTLE ITDQDMFGDA STSLVVPEKV KTPMKSSKTD LQGSASPSKV EGVHTPRQKR STPLKERQLS KPLSERTNSS DSERSPDLGH STQIPRKVVY DQLNQILVSD A

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 420-560 of human PACS1 (NP_060496.2).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:3000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PACS1

Target: PACS1 (phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))

Alternative Name: PACS1 (PACS1 Products)

Synonyms: MRD17 antibody, AI325977 antibody, Pacs-1 antibody, phosphofurin acidic cluster sorting protein 1 antibody, PACS1 antibody, Pacs1 antibody

Background: This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance.,PACS1,MRD17,SHMS,Signal Transduction,Endocrine & Metabolism,Endocrine and metabolic diseases,Obesity,PACS1

Molecular Weight: 104 kDa/109 kDa

Gene ID: 55690

UniProt: Q6VY07