PADI2 antibody (AA 26-210)

Catalog No. ABIN6145163

Product Details anti-PADI2 Antibody

Target: PADI2 (Peptidyl Arginine Deiminase, Type II (PADI2))

Binding Specificity: AA 26-210

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PADI2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: WTDVYSAAPA GAQTFSLKHS EHVWVEVVRD GEAEEVATNG KQRWLLSPST TLRVTMSQAS TEASSDKVTV NYYDEEGSIP IDQAGLFLTA IEISLDVDAD RDGVVEKNNP KKASWTWGPE GQGAILLVNC DRETPWLPKE DCRDEKVYSK EDLKDMSQMI LRTKGPDRLP AGYEIVLYIS MSDSD

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 26-210 of human PADI2 (NP_031391.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PADI2

Target: PADI2 (Peptidyl Arginine Deiminase, Type II (PADI2))

Alternative Name: PADI2 (PADI2 Products)

Synonyms: PADI2 antibody, PAD-H19 antibody, PAD2 antibody, PDI2 antibody, Pdi antibody, Pdi2 antibody, mKIAA0994 antibody, peptidyl arginine deiminase 2 antibody, peptidyl arginine deiminase, type II antibody, protein-arginine deiminase type-2 antibody, peptidyl arginine deiminase, type II S homeolog antibody, PADI2 antibody, padi2 antibody, LOC100357368 antibody, padi2.S antibody, Padi2 antibody

Background: This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes.,PADI2,PAD-H19,PAD2,PDI2,Epigenetics & Nuclear Signaling,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,PADI2

Molecular Weight: 49 kDa/75 kDa

Gene ID: 11240

UniProt: Q9Y2J8