PCSK9 antibody (C-Term)

Catalog No. ABIN6145328

Product Details anti-PCSK9 Antibody

Target: PCSK9 (Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCSK9 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: CCHAPGLECK VKEHGIPAPQ EQVTVACEEG WTLTGCSALP GTSHVLGAYA VDNTCVVRSR DVSTTGSTSE GAVTAVAICC RSRHLAQASQ ELQ

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 600 to the C-terminus of human Proprotein Convertase 9(PCSK9) (NP_777596.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PCSK9

Target: PCSK9 (Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9))

Alternative Name: PCSK9 (PCSK9 Products)

Synonyms: FH3 antibody, HCHOLA3 antibody, LDLCQ1 antibody, NARC-1 antibody, NARC1 antibody, PC9 antibody, AI415265 antibody, AI747682 antibody, Narc1 antibody, proprotein convertase subtilisin/kexin type 9 antibody, proprotein convertase subtilisin/kexin type 9 L homeolog antibody, PCSK9 antibody, pcsk9.L antibody, pcsk9 antibody, Pcsk9 antibody

Background: This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an autocatalytic processing event with its prosegment in the ER and is constitutively secreted as an inactive protease into the extracellular matrix and trans-Golgi network. It is expressed in liver, intestine and kidney tissues and escorts specific receptors for lysosomal degradation. It plays a role in cholesterol and fatty acid metabolism. Mutations in this gene have been associated with autosomal dominant familial hypercholesterolemia. Alternative splicing results in multiple transcript variants.,PCSK9,FH3,HCHOLA3,LDLCQ1,NARC-1,NARC1,PC9,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Ubiquitin,Endocrine & Metabolism,Amino acid metabolism,Lipid Metabolism,Cholesterol Metabolism,Stem Cells,Neural Stem Cells,Cardiovascular,Lipids,PCSK9

Molecular Weight: 20 kDa/74 kDa

Gene ID: 255738

UniProt: Q8NBP7