PLK3 antibody (AA 487-646)

Catalog No. ABIN6145779

Product Details anti-PLK3 Antibody

Target: PLK3 (Polo-Like Kinase 3 (PLK3))

Binding Specificity: AA 487-646

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLK3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VLFNDGTHMA LSANRKTVHY NPTSTKHFSF SVGAVPRALQ PQLGILRYFA SYMEQHLMKG GDLPSVEEVE VPAPPLLLQW VKTDQALLML FSDGTVQVNF YGDHTKLILS GWEPLLVTFV ARNRSACTYL ASHLRQLGCS PDLRQRLRYA LRLLRDRSPA

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 487-646 of human PLK3 (NP_004064.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PLK3

Target: PLK3 (Polo-Like Kinase 3 (PLK3))

Alternative Name: PLK3 (PLK3 Products)

Synonyms: cnk antibody, wu:fi35f10 antibody, fnk antibody, prk antibody, plx3 antibody, MGC89507 antibody, PLK2/3 antibody, NV15469 antibody, Plx3 antibody, CNK antibody, FNK antibody, PRK antibody, Cnk antibody, Fnk antibody, polo-like kinase 3 (Drosophila) antibody, polo like kinase 3 antibody, polo-like kinase 3 antibody, polo-like kinase 3 S homeolog antibody, polo-like kinase 3 L homeolog antibody, Serine/threonine-protein kinase plk-3 antibody, plk3 antibody, PLK3 antibody, LOC100118436 antibody, plk3.S antibody, plk3.L antibody, Plk3 antibody, plk-3 antibody

Background: The protein encoded by this gene is a member of the highly conserved polo-like kinase family of serine/threonine kinases. Members of this family are characterized by an amino-terminal kinase domain and a carboxy-terminal bipartite polo box domain that functions as a substrate-binding motif and a cellular localization signal. Polo-like kinases are important regulators of cell cycle progression. This gene has also been implicated in stress responses and double-strand break repair. In human cell lines, this protein is reported to associate with centrosomes in a microtubule-dependent manner, and during mitosis, the protein becomes localized to the mitotic apparatus. Expression of a kinase-defective mutant results in abnormal cell morphology caused by changes in microtubule dynamics and mitotic arrest followed by apoptosis.,PLK3,CNK,FNK,PLK-3,PRK,Signal Transduction,Kinase,PLK3

Molecular Weight: 71 kDa

Gene ID: 1263

UniProt: Q9H4B4

Pathways: Regulation of long-term Neuronal Synaptic Plasticity