OCT4 antibody
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- Target See all OCT4 (POU5F1) Antibodies
- OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This OCT4 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Immunogen
- A synthetic peptide of human OCT4
- Isotype
- IgG
- Top Product
- Discover our top product POU5F1 Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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NSPc1 promotes cancer stem cell self-renewal by repressing the synthesis of all-trans retinoic acid via targeting RDH16 in malignant glioma." in: Oncogene, Vol. 36, Issue 33, pp. 4706-4718, (2017) (PubMed).
: "NOR1 Suppresses Cancer Stem-Like Cells Properties of Tumor Cells via the Inhibition of the AKT-GSK-3β-Wnt/β-catenin-ALDH1A1 Signal Circuit." in: Journal of cellular physiology, Vol. 232, Issue 10, pp. 2829-2840, (2017) (PubMed).
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NSPc1 promotes cancer stem cell self-renewal by repressing the synthesis of all-trans retinoic acid via targeting RDH16 in malignant glioma." in: Oncogene, Vol. 36, Issue 33, pp. 4706-4718, (2017) (PubMed).
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- Target
- OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
- Alternative Name
- POU5F1 (POU5F1 Products)
- Synonyms
- OCT3 antibody, OCT4 antibody, OTF-3 antibody, OTF3 antibody, OTF4 antibody, Oct-3 antibody, Oct-4 antibody, POU5F1 antibody, gp9 antibody, gp-9 antibody, oct4 antibody, pou2 antibody, POU-2 antibody, cb197 antibody, spg/pou2 antibody, chunp6868 antibody, wu:fd18d06 antibody, NF-A3 antibody, Oct-3/4 antibody, Oct3 antibody, Oct3/4 antibody, Oct4 antibody, Otf-3 antibody, Otf-4 antibody, Otf3 antibody, Otf3-rs7 antibody, Otf3g antibody, Otf4 antibody, POU class 5 homeobox 1 antibody, POU domain, class 5, transcription factor 3 antibody, POU domain, class 5, transcription factor 1 antibody, POU5F1 antibody, pou5f3 antibody, Pou5f1 antibody
- Background
- This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.,POU5F1,OCT3,OCT4,OTF-3,OTF3,OTF4,Oct-3,Oct-4,Epigenetics & Nuclear Signaling,Transcription Factors,RNA Binding,Cell Biology & Developmental Biology,ESC Pluripotency and Differentiation,Stem Cells,Embryonic Stem Cells,Germline Stem Cells,POU5F1
- Molecular Weight
- 30 kDa/38 kDa
- Gene ID
- 5460
- UniProt
- Q01860
- Pathways
- Stem Cell Maintenance
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