PRKACB antibody (AA 1-351)

Catalog No. ABIN6146183

Product Details anti-PRKACB Antibody

Target: PRKACB (Protein Kinase, CAMP Dependent, Catalytic, beta (PRKACB))

Binding Specificity: AA 1-351

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRKACB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: MGNAATAKKG SEVESVKEFL AKAKEDFLKK WENPTQNNAG LEDFERKKTL GTGSFGRVML VKHKATEQYY AMKILDKQKV VKLKQIEHTL NEKRILQAVN FPFLVRLEYA FKDNSNLYMV MEYVPGGEMF SHLRRIGRFS EPHARFYAAQ IVLTFEYLHS LDLIYRDLKP ENLLIDHQGY IQVTDFGFAK RVKGRTWTLC GTPEYLAPEI ILSKGYNKAV DWWALGVLIY EMAAGYPPFF ADQPIQIYEK IVSGKVRFPS HFSSDLKDLL RNLLQVDLTK RFGNLKNGVS DIKTHKWFAT TDWIAIYQRK VEAPFIPKFR GSGDTSNFDD YEEEDIRVSI TEKCAKEFGE F

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-351 of human PRKACB (NP_002722.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PRKACB

Target: PRKACB (Protein Kinase, CAMP Dependent, Catalytic, beta (PRKACB))

Alternative Name: PRKACB (PRKACB Products)

Synonyms: PKACB antibody, XPKAbeta antibody, kin-1 antibody, pkacb antibody, prkacba antibody, PRKACB antibody, prkacb antibody, wu:fz54b03 antibody, zgc:110804 antibody, Pkacb antibody, protein kinase cAMP-activated catalytic subunit beta antibody, protein kinase cAMP-activated catalytic subunit beta S homeolog antibody, protein kinase, cAMP-dependent, catalytic, beta antibody, protein kinase, cAMP-dependent, catalytic, beta b antibody, protein kinase, cAMP dependent, catalytic, beta antibody, PRKACB antibody, prkacb.S antibody, prkacb antibody, Prkacb antibody, prkacbb antibody

Background: The protein encoded by this gene is a member of the serine/threonine protein kinase family. The encoded protein is a catalytic subunit of cAMP (cyclic AMP)-dependent protein kinase, which mediates signalling though cAMP. cAMP signaling is important to a number of processes, including cell proliferaton and differentiation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.,PRKACB,PKA C-beta,PKACB,PKAC-beta,Cancer,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Kinase,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,Cell Cycle,Centrosome,Cytoskeleton,Actins,Endocrine & Metabolism,Lipid Metabolism,AMPK Signaling Pathway,Insulin Receptor Signaling Pathway,Immunology & Inflammation,NF-kB Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,PRKACB

Molecular Weight: 29 kDa/36 kDa/39 kDa/40 kDa/41 kDa/46 kDa

Gene ID: 5567

UniProt: P22694

Pathways: AMPK Signaling, Hedgehog Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Lipid Metabolism