PSMD12 antibody (AA 197-456)
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- Target See all PSMD12 Antibodies
- PSMD12 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))
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Binding Specificity
- AA 197-456
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PSMD12 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- KDYIRTQIIS KKINTKFFQE ENTEKLKLKY YNLMIQLDQH EGSYLSICKH YRAIYDTPCI QAESEKWQQA LKSVVLYVIL APFDNEQSDL VHRISGDKKL EEIPKYKDLL KLFTTMELMR WSTLVEDYGM ELRKGSLESP ATDVFGSTEE GEKRWKDLKN RVVEHNIRIM AKYYTRITMK RMAQLLDLSV DESEAFLSNL VVNKTIFAKV DRLAGIINFQ RPKDPNNLLN DWSQKLNSLM SLVNKTTHLI AKEEMIHNLQ
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 197-456 of human PSMD12 (NP_002807.1).
- Isotype
- IgG
- Top Product
- Discover our top product PSMD12 Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- PSMD12 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))
- Alternative Name
- PSMD12 (PSMD12 Products)
- Synonyms
- wu:fb38a06 antibody, wu:fc34f08 antibody, wu:fc49f02 antibody, PSMD12 antibody, rpn5 antibody, Rpn5 antibody, p55 antibody, 1500002F15Rik antibody, AI480719 antibody, P55 antibody, proteasome 26S subunit, non-ATPase 12 antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 antibody, psmd12 antibody, PSMD12 antibody, Psmd12 antibody
- Background
- The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,PSMD12,Rpn5,p55,STISS,Cell Biology & Developmental Biology,Ubiquitin,PSMD12
- Molecular Weight
- 50 kDa/52 kDa
- Gene ID
- 5718
- UniProt
- O00232
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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