PTPRO antibody (AA 30-300)

Catalog No. ABIN6146468

Product Details anti-PTPRO Antibody

Target: PTPRO (Protein tyrosine Phosphatase, Receptor Type, O (PTPRO))

Binding Specificity: AA 30-300

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPRO antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FHVTVQDDNN IVVSLEASDV ISPASVYVVK ITGESKNYFF EFEEFNSTLP PPVIFKASYH GLYYIITLVV VNGNVVTKPS RSITVLTKPL PVTSVSIYDY KPSPETGVLF EIHYPEKYNV FTRVNISYWE GKDFRTMLYK DFFKGKTVFN HWLPGMCYSN ITFQLVSEAT FNKSTLVEYS GVSHEPKQHR TAPYPPQNIS VRIVNLNKNN WEEQSGNFPE ESFMRSQDTI GKEKLFHFTE ETPEIPSGNI SSGWPDFNSS DYETTSQPYW W

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-300 of human PTPRO (NP_109592.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PTPRO

Target: PTPRO (Protein tyrosine Phosphatase, Receptor Type, O (PTPRO))

Alternative Name: PTPRO (PTPRO Products)

Synonyms: GLEPP1 antibody, RPTP-BK antibody, D28 antibody, PTPBK antibody, PTPROt antibody, PTPU2 antibody, PTPoc antibody, PTPphi antibody, Ptpn15 antibody, R-PTP-O antibody, NPHS6 antibody, PTP-OC antibody, PTP-U2 antibody, PTPROT antibody, protein tyrosine phosphatase, receptor type O antibody, protein tyrosine phosphatase, receptor type, O antibody, PTPRO antibody, Ptpro antibody

Background: This gene encodes a member of the R3 subtype family of receptor-type protein tyrosine phosphatases. These proteins are localized to the apical surface of polarized cells and may have tissue-specific functions through activation of Src family kinases. This gene contains two distinct promoters, and alternatively spliced transcript variants encoding multiple isoforms have been observed. The encoded proteins may have multiple isoform-specific and tissue-specific functions, including the regulation of osteoclast production and activity, inhibition of cell proliferation and facilitation of apoptosis. This gene is a candidate tumor suppressor, and decreased expression of this gene has been observed in several types of cancer.,PTPRO,GLEPP1,NPHS6,PTP-OC,PTP-U2,PTPROT,PTPU2,R-PTP-O,Signal Transduction,PTPRO

Molecular Weight: 43 kDa/47 kDa/67 kDa/134 kDa/138 kDa

Gene ID: 5800

UniProt: Q16827

Pathways: Cell-Cell Junction Organization