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REG4 antibody (AA 23-158)

REG4 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6146859
  • Target See all REG4 Antibodies
    REG4 (Regenerating Islet-Derived Family, Member 4 (REG4))
    Binding Specificity
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 23-158
    Reactivity
    • 20
    • 5
    • 4
    • 2
    • 1
    • 1
    Human
    Host
    • 20
    • 2
    Rabbit
    Clonality
    • 20
    • 2
    Polyclonal
    Conjugate
    • 11
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This REG4 antibody is un-conjugated
    Application
    • 11
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    DIIMRPSCAP GWFYHKSNCY GYFRKLRNWS DAELECQSYG NGAHLASILS LKEASTIAEY ISGYQRSQPI WIGLHDPQKR QQWQWIDGAM YLYRSWSGKS MGGNKHCAEM SSNNNFLTWS SNECNKRQHF LCKYRP
    Cross-Reactivity
    Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 23-158 of human REG4 (NP_114433.1).
    Isotype
    IgG
    Top Product
    Discover our top product REG4 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    REG4 (Regenerating Islet-Derived Family, Member 4 (REG4))
    Alternative Name
    REG4 (REG4 Products)
    Synonyms
    GISP antibody, REG-IV antibody, RELP antibody, 2010002L15Rik antibody, regenerating family member 4 antibody, regenerating islet-derived family, member 4 antibody, Reg4 antibody, REG4 antibody
    Background
    Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP, a member of the regenerating gene family belonging to the calcium (C-type) dependent lectin superfamily, has been found to be involved in malignancy in several different organs including the stomach, colorectum, pancreas and prostate. It is highly expressed in the gastrointestinal tract and markedly up-regulated in colon adenocarcinoma, pancreatic cancer, gastric adenocarcinoma, and inflammatory bowel disease. Expression of the Reg4 in different cell types has been associated with regeneration, cell growth and cell survival, cell adhesion and resistance to apoptosis. REG4 protein overexpression is associated with an unfavorable response to preoperative chemoradiotherapy and may be used as a predictive biomarker clinically. REG4 may play an important role in the development and progression of colorectal cancer, as well as in intestinal morphogenesis and epithelium restitution.,REG4,GISP,REG-IV,RELP,REG4
    Molecular Weight
    14 kDa/18 kDa
    Gene ID
    83998
    UniProt
    Q9BYZ8
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