AGR3 antibody

Catalog No. ABIN614770

Product Details anti-AGR3 Antibody

Target: AGR3 (Anterior Gradient 3 (AGR3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This AGR3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: This antibody recognizes the PLMII epitope of AGR3 (AG3) and AGR2 (AG2) proteins (19-20 kDa), secreted cytoplasmic proteins which can serve as markers of carcinogenesis.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Protein-A affinity chromatography

Purity: > 95 % pure by SDS-PAGE

Immunogen: Purified human AGR3 protein

Clone: AGR3-4

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for AGR3

Target: AGR3 (Anterior Gradient 3 (AGR3))

Alternative Name: AGR3 (AGR3 Products)

Synonyms: AG3 antibody, BCMP11 antibody, HAG3 antibody, PDIA18 antibody, hAG-3 antibody, E030025L21Rik antibody, Gm888 antibody, RGD1565406 antibody, anterior gradient 3, protein disulphide isomerase family member antibody, anterior gradient 3 antibody, AGR3 antibody, Agr3 antibody

Background: AGR2 (Anterior Gradient 2), also known as AG2 (hAG-2, HAG2 in human), or GOB-4, and AGR3 (Anterior Gradient 3), also known as AG3 (hAG-3, HAG3 in human), or BCMP11, are secreted cytoplasmic proteins which are involved in metastasis induction and p53 tumour supressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumours, AGR2 was reported also as a marker of other carcinomas. Xenopus homolog of these proteins is associated with anteroposterior fate determination during early development.Synonyms: AG2, Anterior gradient protein 2 homolog, Anterior gradient protein 3 homolog, BCMP11, HAG-3, HAG3, HPC8, breast cancer membrane protein 11

Gene ID: 155465, 9606

UniProt: Q8TD06