SP100 antibody (AA 181-480)

Catalog No. ABIN6148308

Product Details anti-SP100 Antibody

Target: SP100 (SP100 Nuclear Antigen (SP100))

Binding Specificity: AA 181-480

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SP100 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FRSLTWPPSG SPSHAGTTPP ENGLSEHPCE TEQINAKRKD TTSDKDDSLG SQQTNEQCAQ KAEPTESCEQ IAVQVNNGDA GREMPCPLPC DEESPEAELH NHGIQINSCS VRLVDIKKEK PFSNSKVECQ AQARTHHNQA SDIIVISSED SEGSTDVDEP LEVFISAPRS EPVINNDNPL ESNDEKEGQE ATCSRPQIVP EPMDFRKLST FRESFKKRVI GQDHDFSESS EEEAPAEASS GALRSKHGEK APMTSRSTST WRIPSRKRRF SSSDFSDLSN GEELQETCSS SLRRGSGKED

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 181-480 of human SP100 (NP_001193631.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SP100

Target: SP100 (SP100 Nuclear Antigen (SP100))

Alternative Name: SP100 (SP100 Products)

Synonyms: SP100 antibody, A430075G10Rik antibody, lysp100b antibody, SP140 antibody, SP100 nuclear antigen antibody, nuclear antigen Sp100 antibody, nuclear autoantigen Sp-100 antibody, SP100 antibody, Sp100 antibody, LOC101120993 antibody

Background: This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene, one of which encodes a high-mobility group protein.,SP100,lysp100b,Epigenetics & Nuclear Signaling,Immunology & Inflammation,SP100

Molecular Weight: 50 kDa/53 kDa/78 kDa/100 kDa/101 kDa

Gene ID: 6672

UniProt: P23497

Pathways: Retinoic Acid Receptor Signaling Pathway