SSX2 antibody (AA 1-188)

Catalog No. ABIN6148504

Product Details anti-SSX2 Antibody

Target: SSX2 (Synovial Sarcoma, X Breakpoint 2 (SSX2))

Binding Specificity: AA 1-188

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SSX2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: MNGDDAFARR PTVGAQIPEK IQKAFDDIAK YFSKEEWEKM KASEKIFYVY MKRKYEAMTK LGFKATLPPF MCNKRAEDFQ GNDLDNDPNR GNQVERPQMT FGRLQGISPK IMPKKPAEEG NDSEEVPEAS GPQNDGKELC PPGKPTTSEK IHERSGPKRG EHAWTHRLRE RKQLVIYEEI SDPEEDDE

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-188 of human SSX2 (NP_783629.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SSX2

Target: SSX2 (Synovial Sarcoma, X Breakpoint 2 (SSX2))

Alternative Name: SSX2 (SSX2 Products)

Synonyms: CT5.2 antibody, CT5.2A antibody, HD21 antibody, HOM-MEL-40 antibody, SSX antibody, SSX2 antibody, SSX3 antibody, SSX family member 2 antibody, protein SSX2 antibody, synovial sarcoma, X breakpoint 2 antibody, SSX2 antibody, LOC741661 antibody, Ssx2 antibody

Background: The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX1 and SSX4 family members, have been involved in t(X,18)(p11.2,q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. This gene also has an identical duplicate, GeneID: 727837, located about 45 kb downstream in the opposite orientation on chromosome X.,SSX2,CT5.2,CT5.2A,HD21,HOM-MEL-40,SSX,SSX2

Molecular Weight: 21 kDa/25 kDa

Gene ID: 6757

UniProt: Q16385