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TGS1 antibody (AA 714-853)

TGS1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6149101
  • Target See all TGS1 Antibodies
    TGS1 (Trimethylguanosine Synthase 1 (TGS1))
    Binding Specificity
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 714-853
    Reactivity
    • 17
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 15
    • 2
    Rabbit
    Clonality
    • 15
    • 2
    Polyclonal
    Conjugate
    • 13
    • 2
    • 1
    • 1
    This TGS1 antibody is un-conjugated
    Application
    • 12
    • 9
    • 7
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    RVIAIDIDPV KIALARNNAE VYGIADKIEF ICGDFLLLAS FLKADVVFLS PPWGGPDYAT AETFDIRTMM SPDGFEIFRL SKKITNNIVY FLPRNADIDQ VASLAGPGGQ VEIEQNFLNN KLKTITAYFG DLIRRPASET
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 714-853 of human TGS1 (NP_079107.6).
    Isotype
    IgG
    Top Product
    Discover our top product TGS1 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    TGS1 (Trimethylguanosine Synthase 1 (TGS1))
    Alternative Name
    TGS1 (TGS1 Products)
    Synonyms
    NCOA6IP antibody, PIMT antibody, PIPMT antibody, D4Ertd800e antibody, Ncoa6ip antibody, Pimt antibody, trimethylguanosine synthase 1 antibody, trimethylguanosine synthase 1 L homeolog antibody, TGS1 antibody, Tgs1 antibody, tgs1.L antibody
    Background
    Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m(7G caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7G cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs. Plays a role in transcriptional regulation.,TGS1,NCOA6IP,PIMT,PIPMT,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Nuclear hormone receptors,Cancer,Signal Transduction,TGS1
    Molecular Weight
    96 kDa
    Gene ID
    96764
    UniProt
    Q96RS0
    Pathways
    Mitotic G1-G1/S Phases, Regulation of Lipid Metabolism by PPARalpha, Ribonucleoprotein Complex Subunit Organization
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