THOC7 antibody (AA 1-204)

Catalog No. ABIN6149122

Product Details anti-THOC7 Antibody

Target: THOC7 (THO Complex 7 (THOC7))

Binding Specificity: AA 1-204

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This THOC7 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MGAVTDDEVI RKRLLIDGDG AGDDRRINLL VKSFIKWCNS GSQEEGYSQY QRMLSTLSQC EFSMGKTLLV YDMNLREMEN YEKIYKEIEC SIAGAHEKIA ECKKQILQAK RIRKNRQEYD ALAKVIQHHP DRHETLKELE ALGKELEHLS HIKESVEDKL ELRRKQFHVL LSTIHELQQT LENDEKLSEV EEAQEASMET DPKP

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-204 of human THOC7 (NP_079351.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for THOC7

Target: THOC7 (THO Complex 7 (THOC7))

Alternative Name: THOC7 (THOC7 Products)

Synonyms: RGD1305475 antibody, NIF3L1BP1 antibody, fSAP24 antibody, 1500006O09Rik antibody, 9230101K24Rik antibody, Nif3l1bp1 antibody, THO complex 7 antibody, Thoc7 antibody, THOC7 antibody

Background: Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.,THOC7,NIF3L1BP1,fSAP24,hTREX30,Epigenetics & Nuclear Signaling,THOC7

Molecular Weight: 23 kDa

Gene ID: 80145

UniProt: Q6I9Y2