TNFRSF10A antibody (AA 269-468)

Catalog No. ABIN6149302

Product Details anti-TNFRSF10A Antibody

Target: TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))

Binding Specificity: AA 269-468

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNFRSF10A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GGDPKCMDRV CFWRLGLLRG PGAEDNAHNE ILSNADSLST FVSEQQMESQ EPADLTGVTV QSPGEAQCLL GPAEAEGSQR RRLLVPANGA DPTETLMLFF DKFANIVPFD SWDQLMRQLD LTKNEIDVVR AGTAGPGDAL YAMLMKWVNK TGRNASIHTL LDALERMEER HAREKIQDLL VDSGKFIYLE DGTGSAVSLE

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 269-468 of human TNFRSF10A (NP_003835.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TNFRSF10A

Target: TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))

Alternative Name: TNFRSF10A (TNFRSF10A Products)

Synonyms: APO2 antibody, CD261 antibody, DR4 antibody, TRAILR-1 antibody, TRAILR1 antibody, TNFRSF10A antibody, TNF receptor superfamily member 10a antibody, tumor necrosis factor receptor superfamily member 26 antibody, tumor necrosis factor receptor superfamily, member 10a antibody, TNFRSF10A antibody, LOC510798 antibody

Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.,TNFRSF10A,APO2,CD261,DR4,TRAILR-1,TRAILR1,Cell Biology & Developmental Biology,Apoptosis,Death Receptor Signaling Pathway,Immunology & Inflammation,CD markers,Cytokines,TNF,NF-kB Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TNFRSF10A

Molecular Weight: 50 kDa

Gene ID: 8797

UniProt: O00220

Pathways: Apoptosis, Positive Regulation of Endopeptidase Activity