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TRPM2 antibody (AA 900-1000)
TRPM2
Reactivity: Human
WB, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-TRPM2 Antibody
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Target
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TRPM2
(Transient Receptor Potential Cation Channel, Subfamily M, Member 2 (TRPM2))
Binding Specificity
All epitopes for TRPM2 antibodies
AA 900-1000
Reactivity
All reactivities for TRPM2 antibodies
Human
Host
All hosts for TRPM2 antibodies
Rabbit
Clonality
All clonalities for TRPM2 antibodies
Polyclonal
Conjugate
All conjugates for TRPM2 antibodies
This TRPM2 antibody is un-conjugated
Application
All applications for TRPM2 antibodies
Western Blotting (WB), Immunofluorescence (IF)
Sequence
SLDFILFCLR LMHIFTISKT LGPKIIIVKR MMKDVFFFLF LLAVWVVSFG VAKQAILIHN ERRVDWLFRG AVYHSYLTIF GQIPGYIDGV NFNPEHCSPN G
Cross-Reactivity
Mouse, Rat
Characteristics
Polyclonal Antibodies
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 900-1000 of human TRPM2 (NP_003298.1).
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000,IF,1:50 - 1:100
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for TRPM2
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Target
TRPM2
(Transient Receptor Potential Cation Channel, Subfamily M, Member 2 (TRPM2))
Alternative Name
TRPM2 (TRPM2 Products )
Synonyms
EREG1 antibody, KNP3 antibody, LTRPC2 antibody, NUDT9H antibody, NUDT9L1 antibody, TRPC7 antibody, Trpm2-predicted antibody, TRPM2 antibody, si:ch73-263b18.1 antibody, 9830168K16Rik antibody, C79133 antibody, Trp7 antibody, Trrp7 antibody, transient receptor potential cation channel subfamily M member 2 antibody, transient receptor potential cation channel, subfamily M, member 2 antibody, transient receptor potential cation channel subfamily C member 7 antibody, TRPM2 antibody, Trpm2 antibody, trpm2 antibody, TRPC7 antibody
Background
The protein encoded by this gene forms a tetrameric cation channel that is permeable to calcium, sodium, and potassium and is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. Additional transcript variants of this gene have been described, but their full-length nature is not known.,TRPM2,EREG1,KNP3,LTRPC2,LTrpC-2,NUDT9H,NUDT9L1,TRPC7,Epigenetics & Nuclear Signaling,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Neuroscience,Calcium Signaling,TRPM2
Molecular Weight
95 kDa/165 kDa/171 kDa
Gene ID
7226
UniProt
O94759
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