UMPS antibody (AA 181-480)

Catalog No. ABIN6149928

Product Details anti-UMPS Antibody

Target: UMPS (Uridine Monophosphate Synthetase (UMPS))

Binding Specificity: AA 181-480

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UMPS antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EILEQQKKVD AETVGRVKRF IQENVFVAAN HNGSPLSIKE APKELSFGAR AELPRIHPVA SKLLRLMQKK ETNLCLSADV SLARELLQLA DALGPSICML KTHVDILNDF TLDVMKELIT LAKCHEFLIF EDRKFADIGN TVKKQYEGGI FKIASWADLV NAHVVPGSGV VKGLQEVGLP LHRGCLLIAE MSSTGSLATG DYTRAAVRMA EEHSEFVVGF ISGSRVSMKP EFLHLTPGVQ LEAGGDNLGQ QYNSPQEVIG KRGSDIIIVG RGIISAADRL EAAEMYRKAA WEAYLSRLGV

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 181-480 of human UMPS (NP_000364.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for UMPS

Target: UMPS (Uridine Monophosphate Synthetase (UMPS))

Alternative Name: UMPS (UMPS Products)

Synonyms: zgc:55702 antibody, zgc:55723 antibody, UMPS antibody, OPRT antibody, 1700095D23Rik antibody, AA408257 antibody, AL033308 antibody, BB164745 antibody, Orotidine 5'-phosphate decarboxylase antibody, uridine monophosphate synthetase antibody, uridine monophosphate synthetase L homeolog antibody, uridine 5'-monophosphate synthase antibody, umps-1 antibody, umps antibody, umps.L antibody, UMPS antibody, LOC100556619 antibody, Umps antibody

Background: This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.,UMPS,OPRT,Epigenetics & Nuclear Signaling,Endocrine & Metabolism,Nucleotide metabolism,Purine and pyrimidine synthesis,UMPS

Molecular Weight: 22 kDa/33 kDa/42 kDa/52 kDa

Gene ID: 7372

UniProt: P11172

Pathways: Ribonucleoside Biosynthetic Process