ZBTB48 antibody (AA 1-280)

Catalog No. ABIN6150386

Product Details anti-ZBTB48 Antibody

Target: ZBTB48 (Zinc Finger and BTB Domain Containing 48 (ZBTB48))

Binding Specificity: AA 1-280

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZBTB48 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MDGSFVQHSV RVLQELNKQR EKGQYCDATL DVGGLVFKAH WSVLACCSHF FQSLYGDGSG GSVVLPAGFA EIFGLLLDFF YTGHLALTSG NRDQVLLAAR ELRVPEAVEL CQSFKPKTSV GQAAGGQSGL GPPASQNVNS HVKEPAGLEE EEVSRTLGLV PRDQEPRGSH SPQRPQLHSP AQSEGPSSLC GKLKQALKPC PLEDKKPEDC KVPPRPLEAE GAQLQGGSNE WEVVVQVEDD GDGDYMSEPE AVLTRRKSNV IRKPCAAEPA LSAGSLAAEP

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ZBTB48 (NP_005332.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ZBTB48

Target: ZBTB48 (Zinc Finger and BTB Domain Containing 48 (ZBTB48))

Alternative Name: ZBTB48 (ZBTB48 Products)

Synonyms: ZBTB48 antibody, HKR3 antibody, ZNF855 antibody, pp9964 antibody, 0610011D15Rik antibody, AI327031 antibody, Hkr3 antibody, zinc finger and BTB domain containing 48 antibody, zinc finger and BTB domain containing 48 S homeolog antibody, ZBTB48 antibody, Zbtb48 antibody, zbtb48.S antibody

Background: Telomere-binding protein that acts as a regulator of telomere length. Directly binds the telomeric double-stranded 5'-TTAGGG-3' repeat. Preferentially binds to telomeres that have a low concentration of shelterin complex and acts as a regulator of telomere length by initiating telomere trimming, a process that prevents the accumulation of aberrantly long telomeres. Also acts as a transcription regulator that binds to promoter regions. Regulates expression of a small subset of genes, including MTFP1. Regulates expression the J and/or S elements in MHC II promoter. Acts as a negative regulator of cell proliferation by specifically activating expression of ARF, a tumor suppressor isoform of CDKN2A.,ZBTB48,HKR3,TZAP,ZNF855,pp9964,Epigenetics & Nuclear Signaling,Transcription Factors,ZBTB48

Molecular Weight: 77 kDa

Gene ID: 3104

UniProt: P10074