TRPV2 antibody (Ser157)

Catalog No. ABIN615540

Product Details anti-TRPV2 Antibody

Target: TRPV2 (Transient Receptor Potential Cation Channel, Subfamily V, Member 2 (TRPV2))

Binding Specificity: Ser157

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRPV2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Sequence: R-V-SP-N-A

Specificity: This antibody detects TRPV2 / Vanilloid receptor-like protein 1.

Cross-Reactivity (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogen: Synthesized non-phosphopeptide derived from human VASP around the phosphorylation site of serine 157

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.71 mg/mL

Buffer: 0.1 M Tris-glycine, pH 7, 10 % Glycerol containing 0.01 % Thimerosal as preservative

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for TRPV2

Target: TRPV2 (Transient Receptor Potential Cation Channel, Subfamily V, Member 2 (TRPV2))

Alternative Name: TRPV2 / VRL1 (TRPV2 Products)

Synonyms: TRPV2 antibody, VRL antibody, VRL-1 antibody, VRL1 antibody, Vrl1 antibody, GRC antibody, OTRPC2 antibody, transient receptor potential cation channel subfamily V member 2 antibody, transient receptor potential cation channel, subfamily V, member 2 antibody, TRPV2 antibody, LOC100540299 antibody, Trpv2 antibody

Background: Transient Receptor Potential Vanilloid (TRPV) channels are widely expressed in both sensory and nonsensory cells. TRPV2, a member of transient receptor potential ion channels, responds to high-threshold noxious heat (with a threshold of approximately 52 degrees C), but neither to capsaicin nor to proton. TRPV2 transcripts are not restricted to the sensory nervous system, indicating that this channel may be activated by stimuli other than heat. It has been proposed that responses to noxious heat involve these related, but distinct, ion-channel subtypes that together detect a range of stimulus intensities.Synonyms: OTRPC2, Osm-9-like TRP channel 2, Transient receptor potential cation channel subfamily V member 2, VRL, VRL-1, Vanilloid receptor-like protein 1

Gene ID: 51393

NCBI Accession: NP_057197

UniProt: Q9Y5S1

Pathways: Regulation of Cell Size