KCTD11 antibody (Internal Region)

Catalog No. ABIN615971

Product Details anti-KCTD11 Antibody

Target: KCTD11 (Potassium Channel Tetramerisation Domain Containing 11 (KCTD11))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat, Cow, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This KCTD11 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequence: C-PEVEYGRLGL QP

Specificity: Recognizes KCTD11

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Canine (Dog) and Cow.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_001002914.1. Genename: KCTD11

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for KCTD11

Target: KCTD11 (Potassium Channel Tetramerisation Domain Containing 11 (KCTD11))

Alternative Name: KCTD11 (KCTD11 Products)

Synonyms: KCTD11 antibody, AF465352 antibody, Ren antibody, C17orf36 antibody, KCASH1 antibody, REN antibody, REN/KCTD11 antibody, potassium channel tetramerization domain containing 11 antibody, potassium channel tetramerisation domain containing 11 antibody, KCTD11 antibody, Kctd11 antibody

Background: The KCTD11 gene encodes a protein that has been identified as a suppressor of Hedgehog signaling. Its inactivation might lead to a deregulation of the tumor promoting Hedgehog pathway in medulloblastoma.Synonyms: BTB/POZ domain-containing protein KCTD11, C17orf36, REN

Gene ID: 147040

NCBI Accession: NP_001002914

UniProt: Q693B1

Pathways: Hedgehog Signaling