Uroplakin 3A antibody (AA 260-279) (CF®647)

Catalog No. ABIN6168091

Product Details anti-Uroplakin 3A Antibody (CF®647)

Target: Uroplakin 3A (UPK3A)

Binding Specificity: AA 260-279

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Uroplakin 3A antibody is conjugated to CF®647

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Purpose: Polyclonal-anti-UPK3A (Uroplakin-3A) (Rabbit-PAb), CF647 Conjugate

Characteristics: Uroplakin-3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. The protein may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. UPK3A also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. UPK3A has been shown as a helpful marker for the detection of bladder cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: A synthetic peptide, aa260-279 (GASESSYTSVNRGPPLDRAE) of human UPK3A

Clone: PAb

Isotype: IgG

Application Details

Application Notes: Flow Cytometry 0.5-1 μg/million cells/0.1 mL

• Immunofluorescence 1-2 μg/mL
• Western blotting 0.5-1 μg/mL
• Optimal dilution for a specific application should be determined by user

Comment:

HEK293 cells or bladder carcinoma

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Target Details for Uroplakin 3A

Target: Uroplakin 3A (UPK3A)

Alternative Name: -UPK3A (Uroplakin-3A) (-) (UPK3A Products)

Synonyms: UP3A antibody, UPIII antibody, UPIIIA antibody, UPK3 antibody, upk3 antibody, upiii antibody, MGC75921 antibody, 1110017C07Rik antibody, UP3a antibody, Upk3 antibody, up3a antibody, upiiia antibody, upk3a antibody, xUPIII antibody, uroplakin 3A antibody, uroplakin 3 antibody, uroplakin 3A L homeolog antibody, UPK3A antibody, upk3a antibody, Upk3a antibody, LOC100008738 antibody, upk3a.L antibody

Background: UP3a, UPIIIA, UPK3A, Uroplakin III (UPIII), Uroplakin3A

Molecular Weight: ~30 kDa

Gene ID: 7380, 632787

UniProt: O75631