EPX antibody (CF®568)

Catalog No. ABIN6173742

Product Details anti-EPX Antibody (CF®568)

Target: EPX (Eosinophil Peroxidase (EPX))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EPX antibody is conjugated to CF®568

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Purpose: Mouse Monoclonal anti-Eosinophil Peroxidase (EPO104), CF568 Conjugate

Characteristics: Peripheral blood granulocytes are classified into neutrophils, basophils and eosinophils according to the staining characteristics of their cytoplasmic granules. Granule proteins are released by physiologic and pharmacologic stimuli and play important roles in both normal and pathological host immune responses. Eosinophil major basic protein and eosinophil peroxidase (EPX) are granule proteins specific to the eosinophil. AHE-1 recognizes human EPX, a granule protein specific to eosinophils. It does not cross-react with eosinophil major basic protein, elastase, cathepsin G, esterase N, thrombin, plasmin, kallikrein, lactoferrin, or transferrin. This MAb stains eosinophils only and does not stain other peripheral blood cells, including platelets, neutrophils, monocytes, lymphocytes or red blood cells. Human EPX gene product can form a tetramer of two light chains and two heavy chains. Other peroxidase family members include myeloperoxidase (MPO), lactoperoxidase (LPO), and thyroid peroxidase (TPO). Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Human eosinophils from a patient with hypereosinophilic syndrome

Clone: EPO104

Isotype: IgG1 kappa

Application Details

Application Notes: Immunofluorescence 0.5-1 μg/mL

• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Optimal dilution for a specific application should be determined by user

Comment:

MCF-7 cells. Tonsil

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Target Details for EPX

Target: EPX (Eosinophil Peroxidase (EPX))

Alternative Name: Eosinophil Peroxidase (EPX Products)

Synonyms: EPX antibody, pmr-1 antibody, EPO antibody, EPP antibody, EPX-PEN antibody, eosinophil peroxidase antibody, eosinophil peroxidase L homeolog antibody, LOC788751 antibody, EPX antibody, epx.L antibody, Epx antibody

Background: Eosinophil peroxidase heavy chain, EPER, EPO, EPP, EPX, EPX PEN, PERE

Molecular Weight: 70 kDa (55 kDa-Heavy Chain, 15 kDa-Light Chain)

Gene ID: 8288, 279259

UniProt: P11678