CD1b antibody

Catalog No. ABIN6176159

Product Details anti-CD1b Antibody

Target: CD1b (CD1B)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD1b antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Purpose: Mouse Monoclonal anti-CD1b (RIV12), Purified, BSA-free

Characteristics: The mouse monoclonal antibody recognizes CD1b, a 44 kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Purification: Purified

Immunogen: Human peripheral lymphocytes

Clone: RIV12

Isotype: IgG1 kappa

Application Details

Application Notes: Immunofluorescence 0.5-1 μg/mLFlow Cytometry 0.5-1 μg/million cells/0.1 mL

Comment:

MOLT4 cells. Human thymus.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS (no BSA, no azide)

Preservative: Azide free

Target Details for CD1b

Target: CD1b (CD1B)

Alternative Name: CD1b (CD1B Products)

Synonyms: CD1 antibody, CD1A antibody, R1 antibody, CD1B3 antibody, CD1B antibody, CD1-b antibody, CD1b molecule antibody, T-cell surface glycoprotein CD1b-3 antibody, CD1b1 molecule antibody, T-cell surface glycoprotein CD1b1 antibody, CD1B antibody, LOC443423 antibody, CD1B1 antibody, LOC100720602 antibody

Background: A1 domain, CD1B, Cortical thymocyte antigen CD1B, hTa1 thymocyte antigen, Ly38, T cell surface glycoprotein CD1b, T6/Leu6

Molecular Weight: 49 kDa

Gene ID: 910, 1310

UniProt: P29016