Tachykinin, Precursor 1 (TAC1) antibody

Details for Product No. ABIN617879, Supplier: Log in to see
Antigen
  • Hs.2563
  • NK2
  • NKNA
  • NPK
  • TAC2
  • PPTA3
  • Ppt5fl
  • RATPPTA3
  • TAC
  • TAC1
  • 4930528L02Rik
  • NK-1
  • NK1
  • Nkna
  • PPT-A
  • PPTA
  • SP
  • PPT
  • beta-PPT-A
  • NKA
  • nk2
  • nkna
  • npk
  • tac1
  • tac2
  • tachykinin
  • tachykinin precursor 1
  • tachykinin, precursor 1
  • tachykinin 1
  • tachykinin precursor 1 L homeolog
  • TAC1
  • Tac1
  • tac1
  • tac1.L
Reactivity
Bird (Avian), Bream (Sparus aurata), Bullfrog (Rana catesbeiana), Cat (Feline), Chicken, Columbina passerina (Common ground-dove), Dasyatis akajei (Red stingray) (Trygon akajei), Dog (Canine), Dogfish (Squalus), Dolphin, Fish, Frog, Gerbil, Goat, Goldfish, Guinea Pig, Hamster, Horse (Equine), Human, Lamprey, Microtus arvalis (Common vole) (Field vole), Monkey, Monodon monoceros (Narwhal), Mouse (Murine), Mudpuppy (Necturus), Parrot (Ara), Pig (Porcine), Pigeon, Quail, Rabbit, Rat (Rattus), Salmon (Salmonidae), Sheep (Ovine), Snail, Squirrel, Starfish (Marthasterias), Sturgeon (Acipenser), Three-spined Stickleback (Gasterosteus aculeatus), Trout, Turtle, Zebra finch (Taeniopygia guttata), Zebrafish (Danio rerio)
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Host
Rabbit
157
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Clonality
Polyclonal
Conjugate
Un-conjugated
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Application
Immunoelectron Microscopy (IEM), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC)
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Options
Supplier
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Supplier Product No.
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Immunogen Substance P
Isotype IgG
Cross-Reactivity Mammalian
Characteristics The Substance P antiserum was quality control tested using standard immunohistochemical methods. The antiserum demonstrates strongly positive labeling of rat substantia nigra and spinal cord using biotin/avidin-HRP techniques. Recommended primary dilutions are 1/500-1/1000 in PBS/0.3 % Triton X-100 - Cy3 Fluorchrome and 1/6000-1/8000 in PBS/0.3 % Triton X-100 - biotin/avidin-HRP Technique. The specificity of the antiserum for Substance P was demonstrated using soluble pre-adsorption with the peptides in question at a final concentration of 10 μg of peptide per mL of diluted antiserum. Substance P immunolabeling was completely abolished by pre-adsorption with Substance P. Pre-adsorption with the following peptides resulted in no reduction of immunostaining: neurokinin A, neurokinin B, somatostatin and neuropeptide K.
Purification Whole Serum
Antigen Tachykinin, Precursor 1 (TAC1)
Alternative Name Substance P (TAC1 Antibody Abstract)
Background Other Names:
Protachykinin-1,PPT,tachykinin peptide hormone, NKA, NKNA, TAC2,tachykinin, precursor 1
Gene ID 6863
Restrictions For Research Use only
Format Liquid
Buffer Contains ≤ 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment After reconstitution, use immediately or refrigerate at 2 - 8 °C up to 2 days. For long-term storage aliquot antibody and freeze at -15 °C or lower. Avoid repeated freeze/thaw cycles.
Supplier Images
Immunohistochemistry (IHC) image for anti-Tachykinin, Precursor 1 (TAC1) antibody (ABIN617879) IHC image of staining in rat spinal cord
Product cited in: Kuo, Liu: "Valproic acid induces aberrant development of striatal compartments and corticostriatal pathways in a mouse model of autism spectrum disorder." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 31, pp. 4458-4471, 2018 (PubMed).

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Mizutani, Takahashi, Okamoto, Karube, Fujiyama: "Substance P effects exclusively on prototypic neurons in mouse globus pallidus." in: Brain structure & function, Vol. 222, pp. 4089-4110, 2017 (PubMed).

Strobel, Sullivan, Stratton, Sah: "Calcium signalling in medial intercalated cell dendrites and spines." in: The Journal of physiology, Vol. 595, pp. 5653-5669, 2017 (PubMed).

McLeod, Kobayashi, Sen, Baghbaderani, Sadi, Ulalia, Behie, Mendez: "Transplantation of GABAergic cells derived from bioreactor-expanded human neural precursor cells restores motor and cognitive behavioral deficits in a rodent model of Huntington's disease." in: Cell transplantation, Vol. 22, Issue 12, pp. 2237-56, 2014 (PubMed).

Shimizu, Mochizuki, Mitsui, Hashitani: "Neurohumoral regulation of spontaneous constrictions in suburothelial venules of the rat urinary bladder." in: Vascular pharmacology, Vol. 60, Issue 2, pp. 84-94, 2014 (PubMed).

Nweeia, Eichmiller, Hauschka, Donahue, Orr, Ferguson, Watt, Mead, Potter, Dietz, Giuseppetti, Black, Trachtenberg, Kuo: "Sensory ability in the narwhal tooth organ system." in: Anatomical record (Hoboken, N.J. : 2007), Vol. 297, Issue 4, pp. 599-617, 2014 (PubMed).

Blais, Mottier, Germain, Bellenfant, Cadau, Berthod: "Sensory neurons accelerate skin reepithelialization via substance P in an innervated tissue-engineered wound healing model." in: Tissue engineering. Part A, Vol. 20, Issue 15-16, pp. 2180-8, 2014 (PubMed).

Sadeghinezhad, Tootian, Latorre, Sorteni, Chiocchetti: "Intrinsic innervation of the Persian squirrel (Sciurus anomalus) ileum." in: Anatomia, histologia, embryologia, Vol. 42, Issue 3, pp. 201-12, 2013 (PubMed).

Nolano, Provitera, Caporaso, Stancanelli, Leandri, Biasiotta, Cruccu, Santoro, Truini: "Cutaneous innervation of the human face as assessed by skin biopsy." in: Journal of anatomy, Vol. 222, Issue 2, pp. 161-9, 2013 (PubMed).

Nakajima, Mori, Nishikawa, Tsuruta, Okuyama, Furukawa: "Psychiatric disorder-related abnormal behavior and habenulointerpeduncular pathway defects in Wnt1-cre and Wnt1-GAL4 double transgenic mice." in: Journal of neurochemistry, Vol. 124, Issue 2, pp. 241-9, 2013 (PubMed).

Mitsui, Hashitani: "Immunohistochemical characteristics of suburothelial microvasculature in the mouse bladder." in: Histochemistry and cell biology, Vol. 140, Issue 2, pp. 189-200, 2013 (PubMed).

Pauza, Saburkina, Rysevaite, Inokaitis, Jokubauskas, Jalife, Pauziene: "Neuroanatomy of the murine cardiac conduction system: a combined stereomicroscopic and fluorescence immunohistochemical study." in: Autonomic neuroscience : basic & clinical, Vol. 176, Issue 1-2, pp. 32-47, 2013 (PubMed).

Kobayashi, Sano, Vannoni, Goto, Suzuki, Oba, Kawasaki, Kanba, Lipp, Murphy, Wolfer, Itohara: "Genetic dissection of medial habenula-interpeduncular nucleus pathway function in mice." in: Frontiers in behavioral neuroscience, Vol. 7, pp. 17, 2013 (PubMed).

Tajima, Fukuda: "Region-specific diversity of striosomes in the mouse striatum revealed by the differential immunoreactivities for mu-opioid receptor, substance P, and enkephalin." in: Neuroscience, Vol. 241, pp. 215-28, 2013 (PubMed).

Yan, Huang, Xie, Xia, Qian, Zhao, Cheng: "Lmx1b controls peptide phenotypes in serotonergic and dopaminergic neurons." in: Acta biochimica et biophysica Sinica, Vol. 45, Issue 5, pp. 345-52, 2013 (PubMed).

Chung, Cho, Bae, Lee, Zhang, Ro: "Peripheral G protein-coupled inwardly rectifying potassium channels are involved in δ-opioid receptor-mediated anti-hyperalgesia in rat masseter muscle." in: European journal of pain (London, England), Vol. 18, Issue 1, pp. 29-38, 2013 (PubMed).

Hsiao, Fu, Ho, Chen, Hsieh: "Promotion of thermal analgesia and neuropeptidergic skin reinnervation by 4-methylcatechol in resiniferatoxin-induced neuropathy." in: The Kaohsiung journal of medical sciences, Vol. 29, Issue 8, pp. 405-11, 2013 (PubMed).

Sadeghinezhad, Sorteni, Di Guardo, DAgostino, Agrimi, Nonno, Chiocchetti: "Neurochemistry of myenteric plexus neurons of bank vole (Myodes glareolus) ileum." in: Research in veterinary science, Vol. 95, Issue 3, pp. 846-53, 2013 (PubMed).

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