Mu Opioid Receptor 1 antibody (Opioid Receptor, mu 1) (AA 384-398)

Details for Product anti-OPRM1 Antibody No. ABIN617908
Antigen
  • LMOR
  • M-OR-1
  • MOP
  • MOR
  • MOR1
  • OPRM
  • MOP-R
  • MOR-1
  • MOR-1O
  • Oprm
  • mor
  • muOR
  • MORA
  • Oprrm1
  • or2
  • ZFOR2
  • OPRM1
  • opioid receptor mu 1
  • opioid receptor, mu 1
  • outer membrane protein OprM
  • OPRM1
  • Oprm1
  • oprm1
  • oprM1
Alternatives
anti-Rat (Rattus) Mu Opioid Receptor 1 antibody for Immunohistochemistry (Frozen Sections)
Epitope
AA 384-398
40
15
13
10
8
8
8
8
4
4
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Cat (Feline), Chicken, Frog, Guinea Pig, Human, Monkey, Mouse (Murine), Rat (Rattus), Starlings (Sturnidae)
135
71
56
10
8
8
3
3
2
2
1
1
1
1
1
1
Host
Rabbit
138
3
3
Clonality
Polyclonal
Conjugate
This Mu Opioid Receptor 1 antibody is un-conjugated
6
5
4
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Application
Immunoelectron Microscopy (IEM), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC)
96
56
49
31
17
14
8
6
5
2
1
1
Options
Immunogen Synthetic rat MOR1 (384-398)
Isotype IgG
Cross-Reactivity Guinea Pig, Human, Mouse (Murine), Rat (Rattus)
Characteristics The Mu Opioid Receptor antiserum was quality control tested using standard immunohistochemical methods. The antiserum demonstrates strongly positive labeling of rat caudate putamen and spinal cord (dorsal horn) using indirect immunofluorescent and biotin/avidin-HRP techniques. Recommended primary dilutions are 1/500 - 1/1000 in PBS/0.3 % Triton X-100 - Cy3 Technique and 1/6000 - 1/10000 in PBS/0.3 % Triton X-100 - Biotin/avidin-HRP Technique. Preadsorption with MOR peptide (384-398) at 10 μg/mL completely eliminates labeling. The specificity of the antiserum was determined by immunolabeling of transfected cells, Western Blot analysis and immunoisolation studies.
Purification Whole Serum
Plasmids, Primers & others Plasmids, Primers & others Mu Opioid Receptor 1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name Opioid Receptor-mu (OPRM1 Antibody Abstract)
Background Other Names:
MOR-1, Mu-type opioid receptor,M-OR1,Mu opiate receptor,Opioid receptor B,MUOR1,M-OR-1, MORA, oprm, opioid receptor, mu 1
Gene ID 25601
Pathways cAMP Metabolic Process, Synaptic Membrane
Restrictions For Research Use only
Format Liquid
Buffer Contains ≤ 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment After reconstitution, use immediately or refrigerate at 2 - 8 °C up to 2 days. For long-term storage aliquot antibody and freeze at -15 °C or lower. Avoid repeated freeze/thaw cycles.
Supplier Images
Immunohistochemistry (IHC) image for anti-Opioid Receptor, mu 1 (OPRM1) (AA 384-398) antibody (ABIN617908) IHC image in the rat striatum.
Product cited in: Kuo, Liu: "Valproic acid induces aberrant development of striatal compartments and corticostriatal pathways in a mouse model of autism spectrum disorder." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 31, pp. 4458-4471, 2018 (PubMed).

Strobel, Sullivan, Stratton, Sah: "Calcium signalling in medial intercalated cell dendrites and spines." in: The Journal of physiology, Vol. 595, pp. 5653-5669, 2017 (PubMed).

Bai, Zhang, Li, Lu, Li, He: "Sex differences in peripheral mu-opioid receptor mediated analgesia in rat orofacial persistent pain model." in: PLoS ONE, Vol. 10, Issue 3, pp. e0122924, 2016 (PubMed).

Xu, Cao, He, Zhu, Yang, Saito, Wang, Yan, Hinton, Zou, Ding, Xia, Yan, Shu, Wu, Yang, Feng, Clegg, DeMarchi, Khan, Tsai, DeMayo, Wu, Tong, Xu: "Estrogen receptor-α in medial amygdala neurons regulates body weight." in: The Journal of clinical investigation, Vol. 125, Issue 7, pp. 2861-76, 2015 (PubMed).

Huerta-Ocampo, Mena-Segovia, Bolam: "Convergence of cortical and thalamic input to direct and indirect pathway medium spiny neurons in the striatum." in: Brain structure & function, Vol. 219, Issue 5, pp. 1787-800, 2014 (PubMed).

Jaremko, Thompson, Reyes, Jin, Ebersole, Jenney, Grigson, Levenson, Berrettini, Van Bockstaele: "Morphine-induced trafficking of a mu-opioid receptor interacting protein in rat locus coeruleus neurons." in: Progress in neuro-psychopharmacology & biological psychiatry, Vol. 50, pp. 53-65, 2014 (PubMed).

Chen, McRoberts, Marvizón: "?-Opioid receptor inhibition of substance P release from primary afferents disappears in neuropathic pain but not inflammatory pain." in: Neuroscience, Vol. 267, pp. 67-82, 2014 (PubMed).

Lu, Evans, Hirano, Liu: "Dual role for Islet-1 in promoting striatonigral and repressing striatopallidal genetic programs to specify striatonigral cell identity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 1, pp. E168-77, 2014 (PubMed).

Kaufmann, Matsui, Jeromin, Nerbonne, Ferraguti: "Kv4.2 potassium channels segregate to extrasynaptic domains and influence intrasynaptic NMDA receptor NR2B subunit expression." in: Brain structure & function, Vol. 218, Issue 5, pp. 1115-32, 2013 (PubMed).

Ena, De Backer, Schiffmann, de Kerchove dExaerde: "FACS array profiling identifies Ecto-5' nucleotidase as a striatopallidal neuron-specific gene involved in striatal-dependent learning." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 20, pp. 8794-809, 2013 (PubMed).

Reyes, Vakharia, Ferraro, Levenson, Berrettini, Van Bockstaele: "Opiate agonist-induced re-distribution of Wntless, a mu-opioid receptor interacting protein, in rat striatal neurons." in: Experimental neurology, Vol. 233, Issue 1, pp. 205-13, 2012 (PubMed).

Horner, Hebbard, Logan, Vanchipurakel, Gilbert: "Activation of mu opioid receptors in the striatum differentially augments methamphetamine-induced gene expression and enhances stereotypic behavior." in: Journal of neurochemistry, Vol. 120, Issue 5, pp. 779-94, 2012 (PubMed).

Wouterlood, Härtig, Groenewegen, Voorn: "Density gradients of vesicular glutamate- and GABA transporter-immunoreactive boutons in calbindinand μ-opioid receptor-defined compartments in the rat striatum." in: The Journal of comparative neurology, Vol. 520, Issue 10, pp. 2123-42, 2012 (PubMed).

Pinard, Mascagni, McDonald: "Medial prefrontal cortical innervation of the intercalated nuclear region of the amygdala." in: Neuroscience, Vol. 205, pp. 112-24, 2012 (PubMed).

Melendez-Ferro, Rice, Roberts, Perez-Costas: "Dual use of immunohistochemistry for film densitometry and light microscopy." in: Journal of neuroscience methods, Vol. 208, Issue 1, pp. 86-91, 2012 (PubMed).

Mandemakers, Snellinx, ONeill, de Strooper: "LRRK2 expression is enriched in the striosomal compartment of mouse striatum." in: Neurobiology of disease, Vol. 48, Issue 3, pp. 582-93, 2012 (PubMed).

Davis, Puhl: "Nr4a1-eGFP is a marker of striosome-matrix architecture, development and activity in the extended striatum." in: PLoS ONE, Vol. 6, Issue 1, pp. e16619, 2011 (PubMed).

Lee, Perez, Wang, Guan, Zhao, Fisher, Guan, Sweitzer, Raja, Tao: "Dynamic temporal and spatial regulation of mu opioid receptor expression in primary afferent neurons following spinal nerve injury." in: European journal of pain (London, England), Vol. 15, Issue 7, pp. 669-75, 2011 (PubMed).

Horner, Gilbert, Noble: "Differential regulation of 5-HT2A receptor mRNA expression following withdrawal from a chronic escalating dose regimen of D-amphetamine." in: Brain research, Vol. 1390, pp. 10-20, 2011 (PubMed).

Amir, Amano, Pare: "Physiological identification and infralimbic responsiveness of rat intercalated amygdala neurons." in: Journal of neurophysiology, Vol. 105, Issue 6, pp. 3054-66, 2011 (PubMed).

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