CD70 antibody

Catalog No. ABIN6185165

Product Details anti-CD70 Antibody

Target: CD70 (CD70 Molecule (CD70))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD70 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Coating (Coat)

Purpose: Mouse Monoclonal anti-CD70 (TNFS7/1026), Purified, BSA-free

Characteristics: This antibody recognizes a protein of 30 kDa, identified as CD70. It is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and B-lymphocytes. It induces proliferation of co-stimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Purification: Purified

Immunogen: Recombinant human CD70 protein

Clone: TNFS7-1026

Isotype: IgG1 kappa

Application Details

Application Notes: Immunohistology (frozen) 0.5-1 μg/mL

• Immunofluorescence 0.5-1 μg/mL
• Immunoprecipitation 0.5-1 μg/500 μg protein lysate
• ELISA For coating, order Ab without BSA
• Optimal dilution for a specific application should be determined by user

Comment:

Raji cells. Lymph node or tonsil.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS (no BSA, no azide)

Preservative: Azide free

Target Details for CD70

Target: CD70 (CD70 Molecule (CD70))

Alternative Name: CD70 (CD70 Products)

Synonyms: CD27LG antibody, Cd27l antibody, Tnfsf7 antibody, CD27L antibody, TNFSF7 antibody, CD70 antigen antibody, CD70 molecule antibody, Cd70 molecule antibody, Cd70 antibody, CD70 antibody

Background: CD27 ligand (CD27L), CD27LG, Ki24, Surface antigen CD70, Tumor necrosis factor (ligand) superfamily, member 7 (TNFSF7)

Molecular Weight: ~30 kDa

Gene ID: 970

UniProt: P32970

Pathways: Cancer Immune Checkpoints