NTRK3 antibody (AA 40-300)

Catalog No. ABIN6218246

Product Details anti-NTRK3 Antibody

Target: NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))

Binding Specificity: AA 40-300

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NTRK3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: KTEINCRRPD DGNLFPLLEG QDSGNSNGNA SINITDISRN ITSIHIENWR SLHTLNAVDM ELYTGLQKLT IKNSGLRSIQ PRAFAKNPHL RYINLSSNRL TTLSWQLFQT LSLRELQLEQ NFFNCSCDIR WMQLWQEQGE AKLNSQNLYC INADGSQLPL FRMNISQCDL PEISVSHVNL TVREGDNAVI TCNGSGSPLP DVDWIVTGLQ SINTHQTNLN WTNVHAINLT LVNVTSEDNG FTLTCIAENV VGMSNASVAL T

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 40-300 of human NTRK3 (NP_001007157.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NTRK3

Target: NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))

Alternative Name: NTRK3 (NTRK3 Products)

Synonyms: TRKC antibody, gp145(trkC) antibody, trkC antibody, AW125844 antibody, Ntrk3_tv3 antibody, TrkC antibody, neurotrophic receptor tyrosine kinase 3 antibody, neurotrophic tyrosine kinase, receptor, type 3 antibody, NTRK3 antibody, Ntrk3 antibody

Background: This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene.,NTRK3,GP145-TrkC,TRKC,gp145(trkC),Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Growth factor,Neuroscience,NTRK3

Molecular Weight: 68 kDa/91 kDa/92 kDa/93 kDa/94 kDa

Gene ID: 4916

UniProt: Q16288

Pathways: RTK Signaling, Neurotrophin Signaling Pathway, Regulation of Cell Size