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CFP antibody (AA 190-469)

CFP Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6221045
  • Target See all CFP Antibodies
    CFP (Complement Factor P (CFP))
    Binding Specificity
    • 15
    • 8
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 190-469
    Reactivity
    • 61
    • 32
    • 9
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 60
    • 6
    • 4
    Rabbit
    Clonality
    • 65
    • 5
    Polyclonal
    Conjugate
    • 25
    • 11
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CFP antibody is un-conjugated
    Application
    • 51
    • 22
    • 19
    • 15
    • 13
    • 8
    • 7
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Sequence
    CPTHGAWATW GPWTPCSASC HGGPHEPKET RSRKCSAPEP SQKPPGKPCP GLAYEQRRCT GLPPCPVAGG WGPWGPVSPC PVTCGLGQTM EQRTCNHPVP QHGGPFCAGD ATRTHICNTA VPCPVDGEWD SWGEWSPCIR RNMKSISCQE IPGQQSRGRT CRGRKFDGHR CAGQQQDIRH CYSIQHCPLK GSWSEWSTWG LCMPPCGPNP TRARQRLCTP LLPKYPPTVS MVEGQGEKNV TFWGRPLPRC EELQGQKLVV EEKRPCLHVP ACKDPEEEEL
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 190-469 of human CFP (NP_001138724.1).
    Isotype
    IgG
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CFP (Complement Factor P (CFP))
    Alternative Name
    CFP (CFP Products)
    Synonyms
    BFD antibody, PFC antibody, PFD antibody, PROPERDIN antibody, BCFG antibody, Pfc antibody, Properdin antibody, complement factor properdin antibody, CFP antibody, Cfp antibody
    Background
    This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.,CFP,BFD,PFC,PFD,PROPERDIN,properdin,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,CFP
    Molecular Weight
    51 kDa
    Gene ID
    5199
    UniProt
    P27918
    Pathways
    Complement System
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