SRRM1 antibody (AA 1-160)

Catalog No. ABIN6221692

Product Details anti-SRRM1 Antibody

Target: SRRM1 (Serine/arginine Repetitive Matrix 1 (SRRM1))

Binding Specificity: AA 1-160

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRRM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MDAGFFRGTS AEQDNRFSNK QKKLLKQLKF AECLEKKVDM SKVNLEVIKP WITKRVTEIL GFEDDVVIEF IFNQLEVKNP DSKMMQINLT GFLNGKNARE FMGELWPLLL SAQENIAGIP SAFLELKKEE IKQRQIEQEK LASMKKQDED KDKRDKEEKE

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human SRRM1 (NP_005830.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:1000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SRRM1

Target: SRRM1 (Serine/arginine Repetitive Matrix 1 (SRRM1))

Alternative Name: SRRM1 (SRRM1 Products)

Synonyms: 160-KD antibody, POP101 antibody, SRM160 antibody, AA407769 antibody, Srm160 antibody, serine and arginine repetitive matrix 1 antibody, serine/arginine repetitive matrix 1 antibody, SRRM1 antibody, Srrm1 antibody

Background: Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10 and basal snRNP (SNRP70 and SNRPA1 factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double- or single-stranded nucleic acid substrates.,SRRM1,160-KD,POP101,SRM160,Epigenetics & Nuclear Signaling,SRRM1

Molecular Weight: 102 kDa

Gene ID: 10250

UniProt: Q8IYB3