GABARAPL1 antibody (AA 1-117)

Catalog No. ABIN6223745

Product Details anti-GABARAPL1 Antibody

Target: GABARAPL1 (GABA(A) Receptor-Associated Protein Like 1 (GABARAPL1))

Binding Specificity: AA 1-117

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABARAPL1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MKFQYKEDHP FEYRKKEGEK IRKKYPDRVP VIVEKAPKAR VPDLDKRKYL VPSDLTVGQF YFLIRKRIHL RPEDALFFFV NNTIPPTSAT MGQLYEDNHE EDYFLYVAYS DESVYGK

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-117 of human GABARAPL1 (NP_113600.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GABARAPL1

Target: GABARAPL1 (GABA(A) Receptor-Associated Protein Like 1 (GABARAPL1))

Alternative Name: GABARAPL1 (GABARAPL1 Products)

Synonyms: gabarapl1 antibody, apg8l antibody, atg8 antibody, atg8l antibody, gec1 antibody, gabarapl1-a antibody, GABARAPL3 antibody, APG8-LIKE antibody, APG8L antibody, ATG8 antibody, ATG8B antibody, ATG8L antibody, GEC1 antibody, Gec1 antibody, 3110025G09Rik antibody, 9130422N19Rik antibody, AI196471 antibody, Apg8l antibody, Atg8l antibody, GECI antibody, GEC-1 antibody, GABA(A) receptor-associated protein like 1 antibody, GABA(A) receptor-associated protein like 1 S homeolog antibody, GABA type A receptor associated protein like 1 antibody, gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1 antibody, gabarapl1 antibody, gabarapl1.S antibody, GABARAPL1 antibody, Gabarapl1 antibody

Background: Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles. While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover.,GABARAPL1,APG8-LIKE,APG8L,ATG8,ATG8B,ATG8L,GEC1,Cell Biology & Developmental Biology,Autophagy,Endocrine & Metabolism,Mitochondrial metabolism,Neuroscience,Regulators,GABARAPL1

Molecular Weight: 14 kDa/17 kDa

Gene ID: 23710

UniProt: Q9H0R8

Pathways: Autophagy