CHMP1B antibody (AA 1-199)

Catalog No. ABIN6224258

Product Details anti-CHMP1B Antibody

Target: CHMP1B (Charged Multivesicular Body Protein 1B (CHMP1B))

Binding Specificity: AA 1-199

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHMP1B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MSNMEKHLFN LKFAAKELSR SAKKCDKEEK AEKAKIKKAI QKGNMEVARI HAENAIRQKN QAVNFLRMSA RVDAVAARVQ TAVTMGKVTK SMAGVVKSMD ATLKTMNLEK ISALMDKFEH QFETLDVQTQ QMEDTMSSTT TLTTPQNQVD MLLQEMADEA GLDLNMELPQ GQTGSVGTSV ASAEQDELSQ RLARLRDQV

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-199 of human CHMP1B (NP_065145.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CHMP1B

Target: CHMP1B (Charged Multivesicular Body Protein 1B (CHMP1B))

Alternative Name: CHMP1B (CHMP1B Products)

Synonyms: C10orf2 antibody, C18-ORF2 antibody, C18orf2 antibody, CHMP1.5 antibody, Vps46-2 antibody, Vps46B antibody, hVps46-2 antibody, 2810405I11Rik antibody, Chmp1b1 antibody, Chmp1.5 antibody, fb10c03 antibody, wu:fb10c03 antibody, zgc:56134 antibody, chromatin modifying protein 1b antibody, hypothetical protein antibody, charged multivesicular body protein 1B antibody, chromatin modifying protein 1B antibody, LOC692931 antibody, PGTG_18215 antibody, CHMP1B antibody, Chmp1b antibody, chmp1b antibody

Background: CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM, Mar 2008],CHMP1B,C10orf2,C18-ORF2,C18orf2,CHMP1.5,Vps46-2,Vps46B,hVps46-2,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,CHMP1B

Molecular Weight: 22 kDa

Gene ID: 57132

UniProt: Q7LBR1