TRPV1 antibody (AA 400-500)

Catalog No. ABIN6224662

Product Details anti-TRPV1 Antibody

Target: TRPV1 (Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1))

Binding Specificity: AA 400-500

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRPV1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IAYSSSETPN RHDMLLVEPL NRLLQDKWDR FVKRIFYFNF LVYCLYMIIF TMAAYYRPVD GLPPFKMEKT GDYFRVTGEI LSVLGGVYFF FRGIQYFLQR R

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 400-500 of human TRPV1 (NP_061197.4).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TRPV1

Target: TRPV1 (Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1))

Alternative Name: TRPV1 (TRPV1 Products)

Synonyms: si:dkey-9e15.2 antibody, VR.5'sv antibody, Vr1 antibody, Vr1l1 antibody, VR1 antibody, OTRPC1 antibody, TRPV1alpha antibody, TRPV1beta antibody, VR-1 antibody, transient receptor potential cation channel, subfamily V, member 1 antibody, transient receptor potential cation channel subfamily V member 1 antibody, trpv1 antibody, Trpv1 antibody, TRPV1 antibody

Background: Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene.,TRPV1,VR1,Neuroscience,TRPV1

Molecular Weight: 94 kDa

Gene ID: 7442

UniProt: Q8NER1

Pathways: Dicarboxylic Acid Transport