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SAFB antibody
SAFB
Reactivity: Human
WB, ICC
Host: Mouse
Monoclonal
unconjugated
Product Details anti-SAFB Antibody
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Target
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SAFB
(Scaffold Attachment Factor B (SAFB))
Reactivity
All reactivities for SAFB antibodies
Human
Host
All hosts for SAFB antibodies
Mouse
Clonality
All clonalities for SAFB antibodies
Monoclonal
Conjugate
All conjugates for SAFB antibodies
This SAFB antibody is un-conjugated
Application
All applications for SAFB antibodies
Western Blotting (WB), Immunocytochemistry (ICC)
Immunogen
Recombinant Protein
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Alternatives
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Application Details
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Application Notes
WB: 1:1000. ICC: 1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Storage
4 °C,-20 °C
Target Details for SAFB
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Target
SAFB
(Scaffold Attachment Factor B (SAFB))
Alternative Name
SAFB1 (SAFB Products )
Synonyms
HAP antibody, HET antibody, SAF-B1 antibody, SAFB1 antibody, 3110021E02Rik antibody, 5330423C17Rik antibody, AU018122 antibody, D18386 antibody, E130307D12 antibody, zgc:55387 antibody, wu:fb40a03 antibody, wu:fd42g06 antibody, SAFB2 antibody, SAFB antibody, scaffold attachment factor B antibody, scaffold attachment factor B S homeolog antibody, SAFB-like transcription modulator antibody, Scaffold attachment factor B antibody, SAFB antibody, Safb antibody, safb antibody, safb.S antibody, LOC5570070 antibody, CpipJ_CPIJ017179 antibody, Bm1_49330 antibody, LOAG_00080 antibody
Background
Binds to scaffold/matrix attachment region (S/MAR) DNA and forms a molecular assembly point to allow the formation of a 'transcriptosomal' complex (consisting of SR proteins and RNA polymerase II) coupling transcription and RNA processing (By similarity). Can function as an estrogen receptor corepressor and can also bind to the HSP27 promoter and decrease its transcription. When associated with RBMX, binds to and stimulates transcription from the SREBF1 promoter (By similarity). Can inhibit cell proliferation.
UniProt
Q15424
Pathways
Intracellular Steroid Hormone Receptor Signaling Pathway
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