PTGDS antibody (C-Term)

Catalog No. ABIN6242475

Product Details anti-PTGDS Antibody

Target: PTGDS (Prostaglandin D2 Synthase (PTGDS))

Binding Specificity: AA 149-182, C-Term

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTGDS antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PTGDS antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 149-182 amino acids from the C-terminal region of human PTGDS.

Clone: RB47844

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for PTGDS

Target: PTGDS (Prostaglandin D2 Synthase (PTGDS))

Alternative Name: PTGDS (PTGDS Products)

Synonyms: 6PGD antibody, GSTS antibody, GSTS1-1 antibody, PGD2 antibody, PGDS antibody, L-PGDS antibody, LPGDS antibody, PDS antibody, PGDS2 antibody, H-PGDS antibody, Ptgds2 antibody, 21kDa antibody, Ptgs3 antibody, PH2DISO antibody, phosphogluconate dehydrogenase antibody, hematopoietic prostaglandin D synthase antibody, prostaglandin D2 synthase antibody, prostaglandin D2 synthase (brain) antibody, prostaglandin D synthase antibody, prostaglandin D2 synthase 21kDa (brain) antibody, PGD antibody, HPGDS antibody, PTGDS antibody, Hpgds antibody, Ptgds antibody, LOC100009453 antibody

Background: Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system.

Molecular Weight: 21029

UniProt: P41222