C1orf38 antibody (C-Term)

Catalog No. ABIN6242717

Product Details anti-C1orf38 Antibody

Target: C1orf38 (Chromosome 1 Open Reading Frame 38 (C1orf38))

Binding Specificity: AA 613-641, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1orf38 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ICB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 613-641 amino acids from the C-terminal region of human ICB1.

Clone: RB24946

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-C1orf38 antibody (ABIN6242717)

Hartweger, Schweighoffer, Davidson, Peirce, Wack, Tybulewicz: "Themis2 is not required for B cell development, activation, and antibody responses." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 2, pp. 700-7, (2014) (PubMed).

Peirce, Brook, Morrice, Snelgrove, Begum, Lanfrancotti, Notley, Hussell, Cope, Wait: "Themis2/ICB1 is a signaling scaffold that selectively regulates macrophage Toll-like receptor signaling and cytokine production." in: PLoS ONE, Vol. 5, Issue 7, pp. e11465, (2010) (PubMed).

Target Details for C1orf38

Target: C1orf38 (Chromosome 1 Open Reading Frame 38 (C1orf38))

Alternative Name: ICB1 (C1orf38 Products)

Synonyms: C1orf38 antibody, ICB-1 antibody, thymocyte selection associated family member 2 antibody, THEMIS2 antibody, Themis2 antibody

Background: Involved in cell adhesion. There are 4 isoforms produced by alternative splicing.

Molecular Weight: 72049

NCBI Accession: NP_001034566, NP_001099026, NP_004839

UniProt: Q5TEJ8