SLC22A2 antibody (N-Term)

Catalog No. ABIN6242877

Product Details anti-SLC22A2 Antibody

Target: SLC22A2 (Solute Carrier Family 22 (Organic Cation Transporter), Member 2 (SLC22A2))

Binding Specificity: AA 57-89, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC22A2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SLC22A2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 57-89 amino acids from the N-terminal region of human SLC22A2.

Clone: RB53175

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000. IHC-P: 1:25. IHC-P: 1:25. FC: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for SLC22A2

Target: SLC22A2 (Solute Carrier Family 22 (Organic Cation Transporter), Member 2 (SLC22A2))

Alternative Name: SLC22A2 (SLC22A2 Products)

Synonyms: OCT2 antibody, Oct2 antibody, Orct2 antibody, OCT2r antibody, rOCT2 antibody, Pou2f2 antibody, OCT2P antibody, oct1 antibody, wu:fc01b11 antibody, zgc:64076 antibody, slc22a2 antibody, solute carrier family 22 member 2 antibody, solute carrier family 22 (organic cation transporter), member 2 antibody, POU class 2 homeobox 2 antibody, solute carrier family 22 (organic cation transporter), member 2 L homeolog antibody, SLC22A2 antibody, Slc22a2 antibody, POU2F2 antibody, LOC521027 antibody, slc22a2 antibody, slc22a2.L antibody

Background: Mediates tubular uptake of organic compounds from circulation. Mediates the influx of agmatine, dopamine, noradrenaline (norepinephrine), serotonin, choline, famotidine, ranitidine, histamin, creatinine, amantadine, memantine, acriflavine, 4-[4-(dimethylamino)-styryl]-N-methylpyridinium ASP, amiloride, metformin, N-1-methylnicotinamide (NMN), tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, cisplatin and oxaliplatin. Cisplatin may develop a nephrotoxic action. Transport of creatinine is inhibited by fluoroquinolones such as DX-619 and LVFX. This transporter is a major determinant of the anticancer activity of oxaliplatin and may contribute to antitumor specificity.

Molecular Weight: 62581

UniProt: O15244