UNC93B1 antibody (C-Term)

Catalog No. ABIN6252539

Product Details anti-UNC93B1 Antibody

Target: UNC93B1 (Unc-93 Homolog B1 (UNC93B1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UNC93B1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Protein A Affinity Chromatography

Immunogen: A recombinant protein fragment from the C-terminal portion of UNC93B was used as the immunogen for this antibody.

Isotype: IgG

Application Details

Application Notes: Western blot: 3-6 μg/mL

Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Target Details for UNC93B1

Target: UNC93B1 (Unc-93 Homolog B1 (UNC93B1))

Alternative Name: UNC93B (UNC93B1 Products)

Synonyms: UNC93 antibody, IIAE1 antibody, UNC93B antibody, Unc-93B1 antibody, Unc93b antibody, unc-93 homolog B1, TLR signaling regulator antibody, unc-93 homolog B1 (C. elegans) antibody, UNC93B1 antibody, Unc93b1 antibody

Background: UNC93B is part of the innate immune response via its direct interaction with the intracellular toll-like receptors TLR3, 7, and 9. UNC93B aids in the trafficing of these TLRs from the ER to the endolysosomes, where they bind ligands and initiate immune response. In the absence of UNC93B, these TLRs are unable to respond to foreign stimuli.

Gene ID: 81622

UniProt: Q9H1C4

Pathways: TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades