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CD16 antibody

CD16 Reactivity: Human FACS, ICC Host: Mouse Monoclonal B-E16 unconjugated

Catalog No. ABIN6253847

Datasheet as PDF

Target See all CD16 Antibodies

CD16
Reactivity
127

26

20

20

20

9

8

8

7

4

2

2

2

2

2

2

2

1

1

1
Human
Host
110

29

14

1
Mouse
Compatible Secondaries
Clonality
126

26

1
Monoclonal
Conjugate
55

18

13

12

7

7

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD16 antibody is un-conjugated
Application
124

31

28

25

24

23

21

17

5

5

3

3

3

2

2

2

1
Flow Cytometry (FACS), Immunocytochemistry (ICC)

Specificity

B-E16 produces mouse IgG2a immunoglobulins specific for a 50-70 kD antigen which is associated with the IgG FceRI on NK cells, neutrophils, granulocytes and monocytes [3]

Purity

PURE

Clone

B-E16

Isotype

IgG2a

Top Product

Discover our top product CD16 Primary Antibody
anti-CD16 (CD16) antibody
CD16 Reactivity: Human, Non-Human Primate FACS, IP, IHC (fro) Host: Mouse Monoclonal 3G8 unconjugated

anti-CD16 (CD16) antibody (FITC)
CD16 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal LNK16 FITC

anti-CD16 (CD16) antibody
CD16 Reactivity: Human FACS, IP, WB Host: Mouse Monoclonal MEM-154 unconjugated

anti-CD16 (CD16) antibody
CD16 Reactivity: Human, Pig, Non-Human Primate FACS Host: Mouse Monoclonal MEM-168 unconjugated

anti-CD16 (CD16) antibody
CD16 Reactivity: Human FACS, IP, WB, Func Host: Mouse Monoclonal MEM-154 unconjugated

anti-CD16 (CD16) antibody (Biotin)
CD16 Reactivity: Human FACS, IP, WB Host: Mouse Monoclonal MEM-154 Biotin

anti-CD16 (CD16) (AA 17-208) antibody
CD16 Reactivity: Human FACS, WB, IHC, ELISA, ICC, Neut Host: Mouse Monoclonal 2G10A9 unconjugated

anti-CD16 (CD16) antibody
CD16 Reactivity: Human, Non-Human Primate FACS, IP, Func, IHC (fro) Host: Mouse Monoclonal 3G8 unconjugated

anti-CD16 (CD16) antibody (PE-DyLight 594)
CD16 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal 3G8 PE-DyLight 594

anti-CD16 (CD16) antibody
CD16 Reactivity: Human FACS Host: Mouse Monoclonal GRM1 unconjugated

Application Notes

immunohistochemistry on cytospots, immunohistochemistry on frozen tissue

Restrictions

For Research Use only
Format

Liquid

Storage

4 °C
Target

CD16

Alternative Name

CD16 (CD16 Products)

Synonyms

Fcgr3 antibody, Fcgr3a antibody, CD16 antibody, FCGR3 antibody, FCGR3@ antibody, CD16b antibody, FCG3 antibody, FCR-10 antibody, FCRIII antibody, FCRIIIb antibody, FcRIII antibody, Fc fragment of IgG, low affinity IIa, receptor antibody, Fc fragment of IgG, low affinity IIIa, receptor (CD16a) antibody, Fc fragment of IgG receptor IIIb antibody, Fc fragment of IgG receptor IIIa antibody, Fc receptor, IgG, low affinity III antibody, Fc-gamma RIII antibody, Fcgr2a antibody, FCGR3A antibody, FCGR3B antibody, Fcgr3 antibody, FCGR3 antibody

Background

Antigen distribution: CD16 is a low-affinity receptor for aggregated IgG (FcgRIII) [1,2]. The transmembrane form of CD16 is expressed on approximately 15% of peripheral blood lymphocytes and is present on virtually all resting NK cells. It is also found on macrophages and mast cells. It binds IgG complexed to antigens and mediates phagocytosis and antibody-dependent cellular cytotoxicity. On NK cells it mediates signal transduction while the GPI-linked form on neutrophils binds to ligands but is unable to induce any signal or functional effect [1]. Cellular Expression: NK cells, neutrophils, granulocytes, macrophages.

Pathways

Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process