CNGA1 antibody (Internal Region)

Catalog No. ABIN6257068

Product Details anti-CNGA1 Antibody

Target: CNGA1 (Cyclic Nucleotide Gated Channel alpha 1 (CNGA1))

Binding Specificity: Internal Region

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNGA1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: CNGA1 Antibody detects endogenous levels of total CNGA1.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CNGA1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CNGA1

Target: CNGA1 (Cyclic Nucleotide Gated Channel alpha 1 (CNGA1))

Alternative Name: CNGA1 (CNGA1 Products)

Synonyms: CNCG antibody, CNCG1 antibody, CNG-1 antibody, CNG1 antibody, RCNC1 antibody, RCNCa antibody, RCNCalpha antibody, RP49 antibody, CNG antibody, CNGC1 antibody, xcnga1 antibody, CNGA1 antibody, Cncg antibody, HCN antibody, cyclic nucleotide gated channel alpha 1 antibody, cyclic nucleotide gated channel alpha 1 L homeolog antibody, CNGA1 antibody, cnga1.L antibody, Cnga1 antibody

Background:

Description: Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors.

Gene: CNGA1

Molecular Weight: 79 kDa

Gene ID: 1259

UniProt: P29973

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction, Asymmetric Protein Localization