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FGF23 antibody (Internal Region)

FGF23 Reactivity: Human, Rat, Mouse WB, ELISA, IHC, ICC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6257180
  • Target See all FGF23 Antibodies
    FGF23 (Fibroblast Growth Factor 23 (FGF23))
    Binding Specificity
    • 15
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    Human, Rat, Mouse
    Host
    • 53
    • 23
    • 2
    Rabbit
    Clonality
    • 57
    • 21
    Polyclonal
    Conjugate
    • 41
    • 11
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FGF23 antibody is un-conjugated
    Application
    • 42
    • 33
    • 17
    • 11
    • 9
    • 8
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificity
    FGF23 Antibody detects endogenous levels of total FGF23.
    Predicted Reactivity
    Horse,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human FGF23, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product FGF23 Primary Antibody
  • Application Notes
    IF/ICC 1:100-1:500, WB 1:500-1000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    FGF23 (Fibroblast Growth Factor 23 (FGF23))
    Alternative Name
    FGF23 (FGF23 Products)
    Synonyms
    FGF23 antibody, ADHR antibody, FGFN antibody, HPDR2 antibody, HYPF antibody, PHPTC antibody, fibroblast growth factor 23 antibody, fgf23 antibody, FGF23 antibody, Fgf23 antibody
    Background

    Description: Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL (By similarity). Acts directly on the parathyroid to decrease PTH secretion (By similarity). Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization.

    Gene: FGF23

    Molecular Weight
    27 kDa
    Gene ID
    8074
    UniProt
    Q9GZV9
    Pathways
    RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion
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