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IL-11 antibody (N-Term)

IL11 Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6257286
  • Target See all IL-11 (IL11) Antibodies
    IL-11 (IL11) (Interleukin 11 (IL11))
    Binding Specificity
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Human, Mouse, Rat
    Host
    • 46
    • 16
    • 1
    • 1
    Rabbit
    Clonality
    • 47
    • 17
    Polyclonal
    Conjugate
    • 30
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL-11 antibody is un-conjugated
    Application
    • 45
    • 30
    • 17
    • 13
    • 13
    • 10
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB), ELISA
    Specificity
    IL11 Antibody detects endogenous levels of total IL11.
    Predicted Reactivity
    Pig,Bovine,Horse,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human IL11, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product IL11 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Expiry Date
    12 months
  • Target
    IL-11 (IL11) (Interleukin 11 (IL11))
    Alternative Name
    IL11 (IL11 Products)
    Synonyms
    IL11 antibody, AGIF antibody, IL-11 antibody, Il-11 antibody, interleukin 11 antibody, IL11 antibody, Il11 antibody
    Background

    Description: Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3.

    Gene: IL11

    Molecular Weight
    27 kDa
    Gene ID
    3589
    UniProt
    P20809
    Pathways
    JAK-STAT Signaling, Negative Regulation of Hormone Secretion
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