Prokineticin Receptor 1 antibody (N-Term)

Catalog No. ABIN6257438

Product Details anti-Prokineticin Receptor 1 Antibody

Target: Prokineticin Receptor 1 (PROKR1)

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prokineticin Receptor 1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: PKR1 Antibody detects endogenous levels of total PKR1.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PKR1, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for Prokineticin Receptor 1

Target: Prokineticin Receptor 1 (PROKR1)

Alternative Name: PROKR1 (PROKR1 Products)

Synonyms: EG-VEGFR1 antibody, Gpr73 antibody, Pkr1 antibody, GPR73 antibody, GPR73a antibody, PKR1 antibody, ZAQ antibody, PROKR1 antibody, prokineticin receptor 1 antibody, Prokr1 antibody, PROKR1 antibody

Background:

Description: Receptor for prokineticin 1. Exclusively coupled to the G(q) subclass of heteromeric G proteins. Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase. May play a role during early pregnancy.

Gene: PROKR1

Molecular Weight: 45 kDa

Gene ID: 10887

UniProt: Q8TCW9

Pathways: Hedgehog Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma