ZFPM1 antibody (Internal Region)

Catalog No. ABIN6257555

Product Details anti-ZFPM1 Antibody

Target: ZFPM1 (Zinc Finger Protein, Multitype 1 (ZFPM1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZFPM1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: ZFPM1 Antibody detects endogenous levels of total ZFPM1.

Predicted Reactivity: Pig

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ZFPM1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for ZFPM1

Target: ZFPM1 (Zinc Finger Protein, Multitype 1 (ZFPM1))

Alternative Name: ZFPM1 (ZFPM1 Products)

Synonyms: FOG antibody, FOG1 antibody, ZC2HC11A antibody, ZNF408 antibody, ZNF89A antibody, Fog1 antibody, Xfog antibody, fog antibody, fog-1 antibody, fog1 antibody, FOG-1 antibody, si:dkey-20g6.1 antibody, si:dkey-38l12.1 antibody, ZNF469 antibody, ZFPM1 antibody, zinc finger protein, FOG family member 1 antibody, zinc finger protein, multitype 1 antibody, zinc finger protein, FOG family member 1 L homeolog antibody, ZFPM1 antibody, Zfpm1 antibody, zfpm1.L antibody, zfpm1 antibody

Background:

Description: Transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. May be involved in regulation of some genes in gonads. May also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2 (By similarity).

Gene: ZFPM1

Molecular Weight: 104 kDa

Gene ID: 161882

UniProt: Q8IX07