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PSMD11 antibody (Internal Region)

PSMD11 Reactivity: Human, Mouse WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6257765
  • Target See all PSMD11 Antibodies
    PSMD11 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 11 (PSMD11))
    Binding Specificity
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 39
    • 31
    • 22
    • 12
    • 11
    • 7
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Human, Mouse
    Host
    • 39
    Rabbit
    Clonality
    • 39
    Polyclonal
    Conjugate
    • 25
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PSMD11 antibody is un-conjugated
    Application
    • 27
    • 17
    • 16
    • 5
    • 4
    • 3
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    PSMD11 Antibody detects endogenous levels of total PSMD11.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human PSMD11, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product PSMD11 Primary Antibody
  • Application Notes
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    PSMD11 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 11 (PSMD11))
    Alternative Name
    PSMD11 (PSMD11 Products)
    Synonyms
    psmd11 antibody, wu:fb55b06 antibody, zgc:56580 antibody, zgc:77763 antibody, Rpn6 antibody, S9 antibody, p44.5 antibody, 1700089D09Rik antibody, 1810019E17Rik antibody, 2610024G20Rik antibody, 2810055C24Rik antibody, C78232 antibody, P44.5 antibody, proteasome 26S subunit, non-ATPase 11 antibody, proteasome 26S subunit, non-ATPase 11b antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 antibody, PSMD11 antibody, psmd11b antibody, Psmd11 antibody
    Background

    Description: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. In the complex, PSMD11 is required for proteasome assembly. Plays a key role in increased proteasome activity in embryonic stem cells (ESCs): its high expression in ESCs promotes enhanced assembly of the 26S proteasome, followed by higher proteasome activity.

    Gene: PSMD11

    Molecular Weight
    42 kDa
    Gene ID
    5717
    UniProt
    O00231
    Pathways
    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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