HINT1 antibody (Internal Region)
-
- Target See all HINT1 Antibodies
- HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))
-
Binding Specificity
- Internal Region
-
Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This HINT1 antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- HINT1 Antibody detects endogenous levels of total HINT1.
- Predicted Reactivity
- Pig,Zebrafish,Bovine,Horse,Rabbit,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human HINT1, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product HINT1 Primary Antibody
-
-
- Application Notes
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
-
- Target
- HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))
- Alternative Name
- HINT1 (HINT1 Products)
- Synonyms
- hint antibody, pkci-1 antibody, prkcnh1 antibody, HINT antibody, NMAN antibody, PKCI-1 antibody, PRKCNH1 antibody, AA673479 antibody, Hint antibody, Ipk1 antibody, Pkci antibody, Prkci antibody, zgc:103764 antibody, CHPKCI antibody, HINTZ antibody, PKCIZ antibody, histidine triad nucleotide binding protein 1 antibody, histidine triad nucleotide binding protein 1 S homeolog antibody, histidine triad nucleotide binding protein 1-Z antibody, Histidine triad nucleotide-binding protein 1 antibody, HINT1 antibody, hint1 antibody, Hint1 antibody, hint1.S antibody, HINT1Z antibody, hint-1 antibody
- Background
-
Description: Hydrolyzes purine nucleotide phosphoramidates with a single phosphate group, including adenosine 5'monophosphoramidate (AMP-NH2), adenosine 5'monophosphomorpholidate (AMP-morpholidate) and guanosine 5'monophosphomorpholidate (GMP-morpholidate). Hydrolyzes lysyl-AMP (AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase, as well as Met-AMP, His-AMP and Asp-AMP, lysyl-GMP (GMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) and AMP-N-alanine methyl ester. Can also convert adenosine 5'-O-phosphorothioate and guanosine 5'-O-phosphorothioate to the corresponding nucleoside 5'-O-phosphates with concomitant release of hydrogen sulfide. In addition, functions as scaffolding protein that modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex and by the complex formed with MITF and CTNNB1. Modulates p53/TP53 levels and p53/TP53-mediated apoptosis. Modulates proteasomal degradation of target proteins by the SCF (SKP2-CUL1-F-box protein) E3 ubiquitin-protein ligase complex.
Gene: HINT1
- Molecular Weight
- 28 kDa
- Gene ID
- 3094
- UniProt
- P49773
-