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HINT1 antibody (Internal Region)

HINT1 Reactivity: Human, Mouse, Rat WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6257885
  • Target See all HINT1 Antibodies
    HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))
    Binding Specificity
    • 15
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 47
    • 37
    • 21
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 43
    • 4
    Rabbit
    Clonality
    • 44
    • 3
    Polyclonal
    Conjugate
    • 22
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This HINT1 antibody is un-conjugated
    Application
    • 19
    • 15
    • 14
    • 13
    • 9
    • 9
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    HINT1 Antibody detects endogenous levels of total HINT1.
    Predicted Reactivity
    Pig,Zebrafish,Bovine,Horse,Rabbit,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human HINT1, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product HINT1 Primary Antibody
  • Application Notes
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))
    Alternative Name
    HINT1 (HINT1 Products)
    Synonyms
    hint antibody, pkci-1 antibody, prkcnh1 antibody, HINT antibody, NMAN antibody, PKCI-1 antibody, PRKCNH1 antibody, AA673479 antibody, Hint antibody, Ipk1 antibody, Pkci antibody, Prkci antibody, zgc:103764 antibody, CHPKCI antibody, HINTZ antibody, PKCIZ antibody, histidine triad nucleotide binding protein 1 antibody, histidine triad nucleotide binding protein 1 S homeolog antibody, histidine triad nucleotide binding protein 1-Z antibody, Histidine triad nucleotide-binding protein 1 antibody, HINT1 antibody, hint1 antibody, Hint1 antibody, hint1.S antibody, HINT1Z antibody, hint-1 antibody
    Background

    Description: Hydrolyzes purine nucleotide phosphoramidates with a single phosphate group, including adenosine 5'monophosphoramidate (AMP-NH2), adenosine 5'monophosphomorpholidate (AMP-morpholidate) and guanosine 5'monophosphomorpholidate (GMP-morpholidate). Hydrolyzes lysyl-AMP (AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase, as well as Met-AMP, His-AMP and Asp-AMP, lysyl-GMP (GMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) and AMP-N-alanine methyl ester. Can also convert adenosine 5'-O-phosphorothioate and guanosine 5'-O-phosphorothioate to the corresponding nucleoside 5'-O-phosphates with concomitant release of hydrogen sulfide. In addition, functions as scaffolding protein that modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex and by the complex formed with MITF and CTNNB1. Modulates p53/TP53 levels and p53/TP53-mediated apoptosis. Modulates proteasomal degradation of target proteins by the SCF (SKP2-CUL1-F-box protein) E3 ubiquitin-protein ligase complex.

    Gene: HINT1

    Molecular Weight
    28 kDa
    Gene ID
    3094
    UniProt
    P49773
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