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CMKLR1 antibody (Internal Region)

CMKLR1 Reactivity: Human WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6257987
  • Target See all CMKLR1 Antibodies
    CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))
    Binding Specificity
    • 16
    • 15
    • 14
    • 11
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 69
    • 42
    • 24
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 71
    • 3
    • 2
    Rabbit
    Clonality
    • 69
    • 6
    • 1
    Polyclonal
    Conjugate
    • 32
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This CMKLR1 antibody is un-conjugated
    Application
    • 62
    • 29
    • 26
    • 26
    • 20
    • 13
    • 9
    • 9
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    CMKLR1 Antibody detects endogenous levels of total CMKLR1.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human CMKLR1, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product CMKLR1 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Expiry Date
    12 months
  • Target
    CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))
    Alternative Name
    CMKLR1 (CMKLR1 Products)
    Synonyms
    CHEMERINR antibody, ChemR23 antibody, DEZ antibody, RVER1 antibody, Gpcr27 antibody, mcmklr1 antibody, si:ch211-240b21.3 antibody, CMLKR1 antibody, Cmklr-1 antibody, GPCR antibody, chemerin chemokine-like receptor 1 antibody, chemokine-like receptor 1 antibody, CMKLR1 antibody, Cmklr1 antibody, cmklr1 antibody
    Background

    Description: Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).

    Gene: CMKLR1

    Molecular Weight
    42 kDa
    Gene ID
    1240
    UniProt
    Q99788
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