CYP17A1 antibody (Internal Region)

Catalog No. ABIN6258050

Product Details anti-CYP17A1 Antibody

Target: CYP17A1 (Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP17A1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: Cytochrome P450 17A1 Antibody detects endogenous levels of total Cytochrome P450 17A1.

Predicted Reactivity: Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Cytochrome P450 17A1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CYP17A1

Target: CYP17A1 (Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1))

Alternative Name: CYP17A1 (CYP17A1 Products)

Synonyms: cyp17 antibody, CYPXVII antibody, P450c17 antibody, cyp17a1 antibody, P450-C17 antibody, wu:fi13g04 antibody, wu:fi17b11 antibody, wu:fi31c08 antibody, zgc:136516 antibody, zgc:66494 antibody, P45017A1 antibody, CYP17 antibody, CPT7 antibody, P450C17 antibody, S17AH antibody, Cyp17 antibody, p450c17 antibody, cytochrome P450 17A1 antibody, cytochrome P450, family 17, subfamily A, polypeptide 1 antibody, steroidogenic cytochrome P450 17-hydroxylase/lyase antibody, cytochrome P450 family 17 subfamily A member 1 L homeolog antibody, cytochrome P450 family 17 subfamily A member 1 antibody, cytochrome P-450 17 alpha-hydroxylase/C17,20-lyase antibody, cytochrome P450, family 17, subfamily a, polypeptide 1 antibody, cytochrome P450c17 antibody, CpipJ_CPIJ010537 antibody, CpipJ_CPIJ010543 antibody, PTRG_02047 antibody, cyp17a1 antibody, cyp17 antibody, cyp17a1.L antibody, CYP17A1 antibody, Cyp17a1 antibody

Background:

Description: Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty.

Gene: CYP17A1

Molecular Weight: 50 kDa

Gene ID: 1586

UniProt: P05093

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin